PART 8 Flashcards
sporotrichosis agent
2 forms
Agent: Sporothrix schenckii
Dimorphic fungus (2 forms:)
Yeast form → inoculated into wounds
Papules which may exude purulent material (initial form)
Nodules commonly found in the limbs reaching up to the chest area
Mold form
In the environment
sporotrichosis dx
what shape can be found in WBC
Cytology
Giemsa stain
Cigar-shaped yeast inside the WBC
Culture of tissue or exudate
Skin biopsy
Systemic antifungal suspension tx for sporotrichosis
Sodium iodide
Most common skin tumor of horses
Locally invasive fibroblastic neoplasms
Head ears limbs
May arise spontaneously
Or may be found in areas with severe trauma to the skin
suspected causative agent
sarcoids
CA: Bovine papillomavirus (Suspected)
skin bipsy and surgery is recommnede din sarcods t/f
f -Not recommended
Lead to fibroblastic sarcoids
Histopath: whirls or circular formation of fibroblast
Interracing bundle of fibroblast
types of sarcoids
Warts
Benign neglect
Walang gagawin
“Proud flesh”
Tx: Surgical removal of tumors followed by the injections of the BCG vax
verrucous
fibroblastic
types of sarcoids
Flat and circular; not all have bulging appearance
Benign neglect
occult
Skin biopsy and surgery not recommended in occult and verrucous sarcoids.
Can lead to fibroblastic sarcoids
t/f
t
tx of sarcoids
Surgical debulking
BCG (Bacille Calmette Guerin) vaccine
To stimulate immune response (host LOs and NKs) to tumor cells
Flunixin meglumine and Prednisone: given first (pretreatment) to prevent anaphylaxis risk due to vax 30mins before
Every 2-3 weeks for 4 tx
Cisplatin: 100% effective in some reports
benign or malignant
Lesions: nodular, black in appearance
Observed at the ventrum of tail
melanoma
melanoma
breeds predisposed + color + age
arabian
perceheron
Predilected in Gray colored horses
Even in dapple gray horses
Relationship between gray coat color and melanomas ; >15 yrs of age
reporeted to cause regression in tumors (melanoma)
melanomas commonly interfere with the horses function t/f
cimetidin
f- No Tx
Unless tumors interfere with function
Rare that these tumors interfere with horse performance
MOST COMMON NODULAR DZ IN HORSES
2 common proposed causes
nodules common in
EOSINOPHILIC GRANULOMA COMPLEX
reaction on insect bites
Other environmental allergens
Saddle / riding equipment
neck back trum
size variatios f EGC
0.5-1cm
EGC other terms
eosinophilic granuloma with collagen degeneration,
nodular necrobiosis of collagen or
collagenolytic granuloma
EGC: ___due to chronic irritation and chronic insect bites = ____ texture
calcify
rock hard
tx of EGC
Corticosteroids (high doses)
Antibiotics (secondary infections)
Surgical removal
For chronic cases; for calcified lesions
Vesicles: fluid filled lesion <1cm in size
Vesicles → ulcerations/erosions
Suspect vesicle producing disease
MUCOCUTANEOUS VESICULAR DISEASE
lesions on reproductive tract
Transmitted during coitus
PIc: Start at vesicles → ulcers (urethra, penis, vulva) → lack of libido due to pain
causative agent
Equine herpes coital exanthema
Caused by EHV-3 (Equid alphaherpesvirus 3)
digansis of EHV3
appearance of lesions
skin biopsy
virus isolation
tx of EHV3
Mainly symptomatic
Avoid corticosteroids
transmission of EHV3
Coitus
Insects
Fomites
Inhalation
Sore nose and sore mouth
vesicular stomatitis
vesicular stoma:
major serotype
enzootic in 3 places
incubation period
causatve agent
rhabdovirus
Major Serotypes:
New jersey
Indiana
Enzootic in north, central, south america
IP 24-72 H
