part 4 Flashcards
What are the 3 categories of decreased RBC production anemia?
- decreased hemoglobin synthesis: iron deficiency, thalassemia, sideroblastic anemia
- defective DNA synthesis: cobalamin (B12) deficiency, folic acid deficiency
- decreased number of RBC precursors: aplastic, myeolproliferative diseases, chronic diseases, medications/chemo, radiation
What are the 2 categories of hemolytic anemias (increased RBC destruction)?
- hereditary (intrinsic)
- acquired (extrinsic)
What are the blood loss anemias?
- acute: trauma, blood vessel rupture, splenic sequestration crisis
- chronic: gastritis, menstrual flow, hemorrhoids
What are the integumentary manifestations of anemia?
- pallor: decreased hemoglobin and blood flow to the skin
- jaundice: increased concentration of serum bilirubin
- pruritus: increased serum and skin bile salt concentrations
What are the cardiopulmonary manifestations of anemia?
-cardiac output is maintained by increasing HR and stroke volume, and respiratory rate
What are some nursing interventions for patients with fatigue?
- alternate rest and activity
- prioritize activities
- provide assistance
- evaluate nutrition
Explain iron deficiency anemia?
-decreased hemoglobin synthesis
- decrease in hemoglobin synthesis
- very common
- young, poor diet, pregnant very susceptible
- malabsorption (diseases, surgery)
- blood loss: ulcer, diverticulitis, menstrual
- hemolysis
- manifestations: pallor, glossitis, cheilitis (inflamed lips),
- diagnostics: labs, stool blood, endoscopy, colonoscopy
- treat underlying disease
- replace iron: food, supplement, transfusion of packed RBCs
- Drug: oral iron-ferrous sulfate, take with juice, if liquid inject through a straw, iron dextran given IM or IV
Iron deficiency anemia
Who is at risk for iron deficiency anemia?
premenopausal pregnant low SES older adults blood loss
What foods are rich in iron?
soybeans oatmeal raisins eggs shell fish grain bread red meat chicken/turkey green leafy veggies
What do we need to educate pt’s about when they are taking an iron supplement?
- dark green to black stools
- dont take with daily
- foods high in vitamin C promote absorption
- takes 4-6 weeks for Hgb and Hct to return to expected range
- disease involving poor production of Hgb
- decreased erythrocyte production
- hemolysis occurs
- autosomal recessive
thalassemia
- frequently asymptomatic
- moderate anemia: microcytosis and hypochromia (small and pale cells)
- body adapts and no tx needed
thalassemia minor
- life threatening
- physical and mental growth is retarded
- pale and jaundiced
- splenomegaly, hepatomegaly, cardiomyopathy
- symptoms develop in childhood
- hepatitis C due to increased blood transfusions
- no drug or diet is effective
- Tx: blood transfusions with chelating agents, splenectomy
thalassemia major