Part 1 of Chapter 6: Transport in humans! 🫀 Flashcards

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1
Q

What is blood?

A
  • Blood is a fluid tissue.
  • It consists of different types of cells such as red blood cells, white blood cells, and platelets and it is suspended plasma (fluid).
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2
Q

What is haemoglobin?

A
  • Haemoglobin is present in the mammalian red blood cells.
  • It is a red pigment that combines reversibly with oxygen, which enables the red blood cell to transport oxygen from the lungs to the rest of the body.
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3
Q

What is the word equation for haemoglobin and oxygen?

A
  • Haemoglobin (purplish red colour) + Oxygen (O2) –>/<– Oxyghaemoglobin (bright red colour)
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4
Q

What is the physical appearance of a red blood cell?

A
  • The red blood cell is a circular and flattened biconcave disc with its centre, that is thinner than the edges of the red blood cell.
  • Thus, this increases the surface area-to-volume ratio, and it allows the cell to absorb and release oxygen at a faster rate.
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5
Q

What is the advantage of having an absence of a nucleus in the red blood cell?

A
  • The absence of a nucleus in the red blood cell increases its capacity for haemoglobin and thus more oxygen.
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6
Q

What is the advantage of having flexible red blood cells?

A
  • Red blood cells are flexible, and they can change into a bell-shaped structure to flow through small blood vessels easily.
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7
Q

What is the mechanism by which the red blood cell transports oxygen to the cells of the body?

A
  1. In the lungs, oxygen level is higher, and oxygen diffuses from the alveoli into the blood as the blood passes through the lungs.
  2. Oxygen binds to the haemoglobin in red blood cells to form oxyhaemoglobin.
  3. The red blood cells transport oxyhaemoglobin to all of the tissues of the body.
  4. As blood passes through tissues containing very little oxygen, the oxyhaemoglobin releases oxygen.
  5. The oxygen then diffuses into the tissue cells, allowing every cell in the body to receive its oxygen supply.
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8
Q

How does white blood cells play a role in keeping the body healthy?

A
  • White blood cells play a role in keeping the body healthy by fighting diseases.
  • The 2 main types of white blood cells are phagocytes and lymphocytes.
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9
Q

What is the process phagocytosis?

A
  • Phagocytosis Is the process where some white blood cells ingest foreign particles such as bacteria and digests them.
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10
Q

What happens when pathogens enter the blood stream?

A
  • When pathogens enter the bloodstream, they stimulate lymphocytes to produce antibodies that recognise the foreign particles.
  • Antibodies attach to the bacteria and cause the bacterial cell membrane to rupture.
  • They bind to the bacteria and cause them to clump together or agglutinate to facilitate phagocytosis.
  • They also bind to the toxins produced by the bacteria and neutralise them.
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11
Q

What is a blood platelet?

A
  • A blood platelet is a fragment of cytoplasm that plays a part in blood clotting.
  • The clotting of blood helps to seal wounds to reduce excessive blood loss and prevents the entry of foreign particles and infection by pathogens.
  • platelets contain enzymes that aid the conversion of fibrinogen, a soluble plasma protein to insoluble fibrin threads.
  • The fibrin threads then entangles blood cells to form a clot or scab.
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12
Q

What is plasma?

A
  • Plasma is a pale yellowish fluid that is composed of mainly water and a mixture of various dissolved substances.
  • It serves as a transport medium that delivers nutrients and transports waste products for one part of the body to another (organ.)
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13
Q

What are the substances transported by blood?

A
  1. Digested food
    - E.g. Glucose, amino acids, mineral salts, fats, and vitamins.
    Carried from: Intestine.
    Carried to:
    - Other parts of the body.
    - Excessive mineral salts are transported to the kidneys for excretion (passed out of the body through urine/faeces).
  2. Excretory products
    - E.g. Nitrogenous waste and carbon dioxide.
    Carried from: All parts of the body (for both nitrogenous waste and carbon dioxide).
    Carried to:
    - Kidney for nitrogenous waste.
    - Lungs for carbon dioxide.
  3. Hormones
    Carried from: Glands
    - E>g. Sex glands (produce sex hormones)
    Carried to:
    - Target organs
  4. Oxygen, which is transported by haemoglobin in the red blood cells.
    Carried from: Lungs.
    Carried to:
    - All parts of the body for cellular respiration, this ensures the survival of that living thing/human.
    side point:
    - Food substances, excretory products, and hormones are carried in solution in the plasma whereas oxygen is carried in the red blood cells.
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14
Q

What is tissue transplant and organ transplant?

A
  • Tissue/organ transport is the replacement of badly damaged/diseased tissue/organ with a healthy one from a donor.
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15
Q

What are the 4 blood groups that exists in humans?

A
  • A, B, AB and O blood groups.
  • These groupings are based on the types of antigens n the red blood cells and antibodies present in the plasma.
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16
Q

How are antigens and antibodies presented using letters?

A
  • Antigens are represented by capital letters A and B.
  • Antibodies are represented by small letters a and b.
17
Q

What are the representations of blood group A and their antigen and antibody?

A
  1. Blood group A
    Antigen on red blood cell: Antigen A
    Antibody in plasma: Antibody b
18
Q

What are the representations of blood group B and their antigen and antibody?

A
  1. Blood group B
    Antigen on red blood cell: Antigen B
    Antibody in plasma: Antibody a
19
Q

What are the representations of blood group AB and their antigen and antibody?

A
  1. Blood group AB
    Antigen on red blood cell: Antigens A and B
    Antibody in plasma: No antibodies
20
Q

What are the representations of blood group O and their antigen and antibody?

A
  1. Blood group O
    Antigen on red blood cell: No antigens
    Antibody in plasma: Antibodies a and b
21
Q

What happens when the antibodies in the blood plasma of a person react with the antigens in the red blood cells of ANOTHER PERSON?

A
  • When the antibodies in the blood plasma of a person react with the antigens in the red blood cells of another person, the red blood cells AGGLUTINTE or clump together (become bigger).
  • Thus, this becomes fatal when the clumps of red blood cells block small blood vessels and therefore obstruct blood flow throughout the whole body.
22
Q

What are the possible combinations of the donor and recipient in blood transfusions?

A
  • Blood group O can donate blood to blood groups O, A, B, and AB.
  • Blood group A can donate blood to blood groups A and AB.
  • Blood group B can donate blood to blood groups B and AB.
  • Blood group AB can donate blood to ONLY blood group AB.