part 1

Question 1

CAD may evolve to more serious conditions like….

Answer 1

UA: unstable angina
MI: myocardial infarction
-these are referred to as acute coronary syndrome (ACS)

Question 2

What makes up ACS?

Answer 2

UA and MI

Question 3

What is the major cause of CAD?

Answer 3

atherosclerosis

Question 4

CAD is typically _________ until disease process is well advanced.

Answer 4

asymptomatic

Question 5

What can cause atherosclerosis in the artery?

Answer 5

damage from: tobacco, hyperlipidemia, HTN, toxins, DM, homocysteine levels, and infx causing local inflammation

Question 6

Lipids accumulate and migrate into smooth muscle cells. This stage may be reversible.

Answer 6

fatty streak

Question 7

Cholesterol is brought in. Collagen covers the fatty streak. Blood flow is reducedand fissures can develop. Not reversible

Answer 7

fibrous plaque

Question 8

The plaque ruptures and a thrombus forms causing further narrowing or total occlusion of the vessel.

Answer 8

complicated lesion

Question 9

What is the difference between the chronic vs sudden onset of CAD in regards to angiogenesis?

Answer 9

• slow development allows for small arteries to grow (angiogenesis)
• sudden does not

Question 10

What are the stages of CAD?

Answer 10

• chronic endothelial injury
• fatty streak
• fibrous plaque
• complicated lesion