Parkinson's Medications

Question 1

Symptoms of Parkinson’s Disease

Answer 1

1. Tremors
2. Muscle rigidity
3. Bradykinesia
4. Postural instability
5. Affective flattening

Question 2

Cause of Parkinson’s

Answer 2

1. Degeneration & destruction-producing neurons
   a. Substantia nigra portion of brain
2. Corpus striatum
   a. Normally controls unconsciousness muscle movement

Question 3

Rx therapy for Parkinson’s

Answer 3

1. Restores dopamine fxn

2. Blocks Ach

Question 4

RN Implication for Parkinson’s

Answer 4

1. Monitor hypotension & tachycardia
2. Look for symptoms of Rx toxicity
3. Contraindicated in narrow-angle glaucoma

Question 5

Name 2 classification medication for Parkinson’s

Answer 5

1. Dopaminergic

2. Anticholinergic

Question 6

Name 2 Rx for Parkinson’s in Dopaminergic class

Answer 6

1. Larodopa

2. Sinement

Question 7

Mechanism of action for Dopaminergics

Answer 7

Increase biosynthesis of dopamine within nerve terminals

Question 8

Dopaminergic Rx Tx…?

Answer 8

Parkinson’s symptoms

Question 9

Dopaminergic Adverse Effect

Answer 9

1. Dizziness
2. Sleep
3. Dysfunction
4. Constipation
5. Orthostatic Hypotension

Question 10

Name 1 Rx for Parkinson’s Anticholinergic class

Answer 10

1. Cogentin

Question 11

Cogentin mechanism of action

Answer 11

Blocks Ach, inhibits overactive brain

Question 12

Cogentin Tx

Answer 12

Early stages of Parkinson’s

Question 13

Cogentin Adverse Effect

Answer 13

1. Dry mouth
2. Blurred vision
3. Photophobia
4. SNS RESPONSE
5. Tachycardia
6. Urinary retention

Question 14

Cogentin RN Implications & Teaching

Answer 14

1. Wear sunglasses
2. Take c food
3. Avoid alcohol
4. Do not stop taking abruptly

Question 15

Dopaminergic RN Implications & Teaching

Answer 15

1. Increase fiber & fluids
2. Do Not Abruptly stop
3. Avoid foods c pyidoxine