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Pharmacology > GI medication > Flashcards

GI medication Flashcards

1
Q

Antacids Mechanism of Action

A

Neutralizes stomach acid and raises pH level

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2
Q

Antacids Tx

A
  1. Promotes healing of ulcers
  2. Reduces ulcers
  3. Tx hyperacidity
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3
Q

Antacids Adverse Effects

A
  1. Decreases effectiveness of anti-infectives & H2 blockers

2. Increases effectiveness of diazepam & enteric coated drugs

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4
Q

Antacids Implication

A
  1. Contains Ca++, aluminum, Mg & Na+
  2. Do Nnot take w/I 2 hrs of other meds
  3. Watch for electrolyte changes
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5
Q

Name 3 H2 Blockers

A
  1. cimetidine
  2. famotidine
  3. ranitidine
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6
Q

H2 Blocker Mechanism of Action

A

Blocks histamine of parietal cells

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7
Q

H2 Blocker Tx

A
  1. Ulcer
  2. Gastresophageal reflux
  3. Short term fix of hyperacidity
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8
Q

H2 Adverse Effects

A
  1. Diahrreah
  2. Dizziness
  3. Mental confussion
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9
Q

Name 2 Protein Pump Inhibitors (PPI)

A
  1. Lansoprazole (Prevacid)

2,. Pantoprazole (Protonix)

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10
Q

PPI Mechanism of Action

A

Inhibits proton pumps, not allowing secretion of HCl

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11
Q

PPI Tx

A
  1. Ulcer
  2. GERD
  3. Hypersecretory
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12
Q

PPI Adverse Effects

A
  1. Abd upset
  2. Headache
  3. Dizziness
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13
Q

PPI Contraindication

A
  1. H2 Blockers
  2. Warfarin
  3. Antibiotic
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14
Q

PPI Implications

A
  1. Do not crush or chew
  2. Long term use can lead to vitamin B12 deficiency-Anemia
  3. Take on empty stomach 30 min before meal
  4. Teach ways to reduce gastric acidity
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15
Q

Name 1 Mucosal Protectant

A
  1. Sucralfate (Carafate)
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16
Q

Mucosal Protectant Mechanism of Action

A

Reacts c HCl & proteins to form a paste @ the ulcer site

17
Q

MP Tx

A
  1. duodenal ulcer

2. Gastric ulcer

18
Q

MP Adverse Effects

A

Constipation

19
Q

MP Implication

A
  1. -90% of aluminum is not absorbed so watch pt c renal disease
  2. Administer on empty stomach 1 hr BEFORE or 2 hrs AFTER food or other meds
  3. Fluching NG Tube before & after giving

Pharmacology (19 decks)

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