Parkinson's Drugs, Unit III Flashcards

1
Q

Precursor to dopamine, and the inhibitor of its metabolism

A

L-DOPA and carbidopa

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2
Q

Direct Dopaminergic agonists (2)

A

Pramipexole, Ropinirole

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3
Q

Facilitators of endogenous dopamine release

A

Amantidine

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4
Q

Inhibits the acetylcholinergic neurons upregulated in the absence of dopamine

A

Benztropine

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5
Q

Inhibit monoamine Oxidase, and hence increase available dopamine (+ one thing to know)

A

Selegiline (MAO-B inhibitor because MAO-A inhibitors are dangerous)

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6
Q

Inhibits Catechol-O-methyl transferase and prevents L-DOPA breakdown

A

Entacapone

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