Glaucoma Drugs, Unit III

Question 1

Lantaprost

Answer 1

Prostaglandin analogue

• 1st line
• Not clear why but facilitates outflow through accessory pathway

Question 2

Brimonidine

Answer 2

Alpha-Adrenergic Agonist (alpha-2)

• Both increases outflow, and decreases inflow
• Risk of CNS depression, sleep apnea in children, common problems with irritation

Question 3

Timolol

Answer 3

Beta-Blocker-

• 2nd most common medication
• Reduces aqueous humor production, and may also lower blood flow
• Systemic absorption can cause serious parasympathetic-esque side effects

Question 4

Dorzolamide

Answer 4

Carbonic Anhydrase inhibitors

• Inhibits carbonic anhydrase in the ciliary epithelium, reduces production of IOP
• Can cause a bitter taste

Question 5

Pilocarpine

Answer 5

Cholinomimetics

• Not used much anymore
• Contracts the ciliary muscle, causes dilation, increases outflow