Antipsychotic Drugs, Unit IV

Question 1

Chlorpromazine

Answer 1

• Typical Antipsychotic
• Causes lots of autonomic side effects (dry mouth, OSH, sedation)
• Treats bad hiccoughs

Question 2

Haloperidol

Answer 2

• Typical Antipsychotic

- BAD EPSs– acute dystonic reactions

Question 3

Thioridazine

Answer 3

• Typical Antipsychotic
• Retinopathy
• Cardiotoxic
• Mild EPSs

Question 4

Clozapine

Answer 4

• Atypical Antipsychotic
  
  • Weight gain
  • High lipids
  • Low EPSs
• Agranulocytosis
• Lowers sz threshhold
• Use in apathy/blunted affect?

Question 5

Olanzapine

Answer 5

• Atypical Antipsychotic
  
  • Weight gain
  • Diabetes
  • Low EPSs
• Use in patients with agitation/insomnia
• Lowers sz threshhold
• Use in apathy/blunted affect?

Question 6

Quetiapine

Answer 6

• Atypical antipsychotic
  
  • Weight gain
  • Low EPSs, even for atypical
• Use in patients with agitation/insomnia– sometimes a questionable sedative

Question 7

Aripiprazole

Answer 7

• Atypical Antipsychotic
  
  • Surprisingly limited weight gain
• Limited sedation
• Lowest QT prolongation among atypicals
• Partial D2 agonist

Question 8

Risperidone

Answer 8

• Atypical Antipsychotic
  - High EPSs for an atypical
• Limited Sedation