Parkinson's

Question 1

Parkinson’s ddx with dementia is?

Answer 1

dementia with lewy bodies

Question 2

classic 4 signs of Parkinson’s?

Answer 2

bradykinesia
tremor
rigidity
posural instability

Question 3

what’s really effective for tremor rx?

Answer 3

Deep brain stim

Question 4

gait for Parkinson’s?

Answer 4

stooped posture
shuffling gait
decreased arm swing

Question 5

if tremor increase with walking, what does it mean?

Answer 5

likely Parkinson’s

Question 6

how are the turning in Parkinson’s?

Answer 6

on block turns

Question 7

face of parkinson’s called?

Answer 7

hypomimia

blank facies

Question 8

pull test is what?

Answer 8

they stand with back to you and you pulled them back. +ve = retropulsion/festinating gait

Question 9

what happens to eyes for Parkinson’s?

Answer 9

reduced blink rate

impaired saccades - hypometric

Question 10

how does Parkinson’s affect speech?

Answer 10

softer speech

Question 11

idiopathic parkinson’s re rigidity is different how?

Answer 11

assymettry

Question 12

dystonia is? what causes?

Answer 12

abnormal involuntary movements
drug induced (too much dopa)

Question 13

dystonia is?

Answer 13

abnormal movements and postures

complication of levodopa or under lying

Question 14

restless leg syndrome is?

Answer 14

pain in leg at night and can’t describe, relieved with walking

Question 15

key night features of parkinsons’

Answer 15

• REM sleep behaviour disorder

- not turning

Question 16

levodopa side effects?

Answer 16

postural hypotension

nausea, abdo cramping, diarrhoea

Question 17

levodopa complications

Answer 17

wearing off
on-off syndrome
failure to turn on
acute dyskinesia

Question 18

COMT inhibitors do what?

Answer 18

inhibit breakdown of dopamine

Question 19

dopamine agonists side effects?

Answer 19

Impulse control disorders:

compulsive shopping
hypersexuality
gambling

Question 20

Amantadine does what?

Answer 20

helps with dyskinesia, helps release dopamine

used to be influenza Rx

Question 21

what are non-motor features of Parkinson’s disease

Answer 21

constipation
urine freq
orthostatic hypotension

Question 22

causes of acute akinesia in Parkinson’s?

Answer 22

countercurrent illness like UTI, URTI

Question 23

advanced therapies for advanced Parkinson’s?

Answer 23

apomorphine - dopamine agonist
DBS
Levodopa infused directly into jejenum

Question 24

Parkinson’s swallowing?

Answer 24

reduced rate
excess saliva
reduced coordinated swallow

Question 25

mean age of dx for Parkinson’s?

Answer 25

age 70, earlier these days