Parkinson's Flashcards
Parkinson’s ddx with dementia is?
dementia with lewy bodies
classic 4 signs of Parkinson’s?
bradykinesia
tremor
rigidity
posural instability
what’s really effective for tremor rx?
Deep brain stim
gait for Parkinson’s?
stooped posture
shuffling gait
decreased arm swing
if tremor increase with walking, what does it mean?
likely Parkinson’s
how are the turning in Parkinson’s?
on block turns
face of parkinson’s called?
hypomimia
blank facies
pull test is what?
they stand with back to you and you pulled them back. +ve = retropulsion/festinating gait
what happens to eyes for Parkinson’s?
reduced blink rate
impaired saccades - hypometric
how does Parkinson’s affect speech?
softer speech
idiopathic parkinson’s re rigidity is different how?
assymettry
dystonia is? what causes?
abnormal involuntary movements drug induced (too much dopa)
dystonia is?
abnormal movements and postures
complication of levodopa or under lying
restless leg syndrome is?
pain in leg at night and can’t describe, relieved with walking
key night features of parkinsons’
- REM sleep behaviour disorder
- not turning
levodopa side effects?
postural hypotension
nausea, abdo cramping, diarrhoea
levodopa complications
wearing off
on-off syndrome
failure to turn on
acute dyskinesia
COMT inhibitors do what?
inhibit breakdown of dopamine
dopamine agonists side effects?
Impulse control disorders:
compulsive shopping
hypersexuality
gambling
Amantadine does what?
helps with dyskinesia, helps release dopamine
used to be influenza Rx
what are non-motor features of Parkinson’s disease
constipation
urine freq
orthostatic hypotension
causes of acute akinesia in Parkinson’s?
countercurrent illness like UTI, URTI
advanced therapies for advanced Parkinson’s?
apomorphine - dopamine agonist
DBS
Levodopa infused directly into jejenum
Parkinson’s swallowing?
reduced rate
excess saliva
reduced coordinated swallow
mean age of dx for Parkinson’s?
age 70, earlier these days
