Allergies Flashcards

1
Q

allergy investigations?

A

RAST (serologic assays) or skin test

Challenge testing

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2
Q

IgE in vitro assays, while one use these days?

A

CAP-FEIA

Kinda of ELISA

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3
Q

in vitro assays advantages?

A

standardized
GPs can prescribe
more quantitative

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4
Q

gold standard for allergy testing?

A

challenge tests

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5
Q

what drugs can influence post natal?

A

penicillins

paracetomol

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6
Q

mechanism of IgE B-cell production

A

Th2 released IL4 tend to shift B-cells to make IgE

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7
Q

what’s the only good treatment for allergies?

A

immunotherapy subcut injections

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8
Q

what is contraindicated to allergy immunotherapy?

A

betablockade

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9
Q

future immunotherapy?

A

sublingual delivery system

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10
Q

how to give immunotherapy injections?

A

always wait 30 minutes after

give antihistamine prior

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11
Q

anaphylaxis presentation?

A

cardiovascular
respiratory, upper and lower
rash

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12
Q

atypical anaphylaxis

A

older and young: GIT involvement without rash

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13
Q

angioedema is what?

A

deep tissue swelling, esp in larynx

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14
Q

angioedema need allergen to contact mouth to get larynx swelling?

A

Nope. systemic reaction

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15
Q

who are most at risk of dying of anaphylaxis food allergy?

A

12-24 year olds

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16
Q

insect venom anaphylaxis, which creatures?

A

jumper ants
honey bee
european wasps

17
Q

dose for adrenaline for adrenaline

A
  1. 5mg of adrenaline

children: 0.01mg/kg up to 0.5mg

18
Q

mild allergic reactions

A

oral anti-histamines

19
Q

when give adrenaline? after first dose?

A

every 20 minutes : 0.5mg for adults

up to 3 doses

20
Q

treatment protocol for allergic rhinitis

A

nasal corticosteroids
antihistamines
immunotherapy

21
Q

thunderstorm asthma is what?

A

thuderstorms bring up pollens, they burst and allergens are rained down onto allergic ppl.

22
Q

what is an allergen?

A

protein that elicits an IgE response