Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Neuro Pharm > Parkinson Drugs > Flashcards

Parkinson Drugs Flashcards

1
Q

1.5 modules away from spring break…

A

Just saying.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Levodopa/Carbidopa: class

A

Dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Levodopa/Carbidopa: MOA

A

Increase dopamine levels in CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Levodopa/Carbidopa: indictaion

A

Parkinson’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Levodopa/Carbidopa: side effects

A

Early: N/V, anorexia, HOTN
Late: Dyskinesia, sleep attacks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Levodopa/Carbidopa: contraindication

A

Renal/hepatic disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

More than 50% of Pts on Levodpa/Carbidopa develop…

A

Motor fluctuations and dyskinesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Benztropine: class

A

Anticholinergic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Benztropine: MOA

A

Ach receptor inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Benztropine: indication

A

PD, extrapyramidal sxs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Benztropine: side effects

A

Dry mouth, urinary retention, blurred vision, temp insensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Benztropine: contraindication

A

Dementia, urinary retention, glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

There’s good new and bad news about Benztropine. What is it?

A

Good new: it decreases drooling and tremors…

Bad news: it doesn’t really help with bradykinesia, rigidity, or gait disturbances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Amandatine: class

A

NMDA receptor antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Amantadine: MOA

A

Decreases Levodopa injury to NMDA receptos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Amantadine: indictaion

A

Mild PD sxs

17
Q

Amantadine: side effects

A

Livedo reticularis, peripheral edema, orthostatic HOTN

18
Q

Amandtadine: contraindications

A

CKD

19
Q

In what population should Amantadine be avoided?

A

The elderly

20
Q

Eldepryl: class

A

MAO-B inhibitor

21
Q

Eldepryl: MOA

A

Inhibition of MAO-B enzyme results in increased available dopamine in CNS

22
Q

Eldepryl: indication

A

PD, depression

23
Q

Eldepryl: side effects

A

Dyskinesia, confusion, hallucinations

24
Q

Eldepryl: contraindication

A

Bipolar d/o, etoh

25
Q

What is the daily limit of Eldepryl?

A

10mg

26
Q

Requip: class

A

Dopamine agonist

27
Q

Requip: MOA

A

Stimulated D3 receptors directly

28
Q

Requip: indication

A

PD, restless leg syndrome

29
Q

Requip: side effect

A

OCD

30
Q

There are two different ways to use Requip. What are they?

A

Can be used initially as mono therapy.

Later in course, can be used as an add on to Levodopa.

31
Q

Comtan: class

A

COMT inhibitor

32
Q

Comtan: MOA

A

COMT enzyme inhibition result in increased [dopamine] in CNS

33
Q

Comtan: indication

A

PD - used in combo with Levodopa

34
Q

What’s the good news and the bad news about Comtan?

A

Good news: Early on it will decrease Levodopa side effects.

Bad news: That doesn’t last forever.

Neuro Pharm (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions