Migraine Drugs Flashcards

1
Q

Name the two Triptans

A
  1. Replax

2. Imitrex

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2
Q

Replax and Imitrex: MOA

A

Activation of trigeminal pre-synaptic serotonin receptors inhibits release of CGRP and is vasoconstricting.

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3
Q

Anyone know what CGRP is?

A

Anyone?…Anyone?…Beuller?

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4
Q

Replax and Imitrex: indication

A

Migraines with or without aura

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5
Q

Replax and Imitrex: side effects

A

Angina, serotonin syndrome

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6
Q

Replax and Imitrex: contraindications

A

Ischemic heart disease
Cerebrovascular disease
Use of an ergotamine w/in 24 hours

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7
Q

In what form is Replax available?

A

Tablet

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8
Q

What routes of administration are available for Imitrex?

A

PO, IN, SQ

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9
Q

Propanolol: class

A

Nonselective B1/B2 blocker

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10
Q

What is Propanolol doing on our migraine drug list?

A

Don’t get so worked up - it’s used for migraine Px.

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