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Endocrine > Parathyroid & Ca Metabolism Disorders > Flashcards

Parathyroid & Ca Metabolism Disorders Flashcards

1
Q

What is the normal serum Ca range

A

about 8.5 to 10.5 mg/dL

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2
Q

Describe the distribution of Ca in our body

A

99% in bones & 1% in ECF (free ionized Ca helps in action potentials, muscle contraction, hormone secretion, blood coag)

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3
Q

Which endocrine hormones regulate calcium homeostasis

A

PTH, calcitonin, calcitriol

(kidneys, small intestine, liver, bones also regulate)

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4
Q

Describe the relationship of serum calcium & phosphate

A

inversely proportional (controlled by Ca, PTH, calcitriol)

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5
Q

Describe the storage of phosphate in our body

A

Most in our bones, remainder as intracellular components of cells (membrane, DNA, RNA, ATP, ADP, lipids, inorganics)

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6
Q

Describe the action of PTH on serum Ca & phosphate

A

produced by parathyroid glands
- increases serum Ca & decreases serum Phos

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7
Q

Describe the action of Calcitriol on serum Ca & Phosphate

A

From diet, UV light, from liver/kidneys
- increases serum Ca & serum phos

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8
Q

Describe the relationship between PTH & Ca

A

Inversely proportionate

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9
Q

Describe the eitology of hypocalcemia

A
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10
Q

Describe the presentation of hypocalcemia

A
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11
Q

Describe the diagnostics for hypocalemia

A
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12
Q

Describe the treatment of hypocalcemia

A
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13
Q

Describe the etiology of hypercalcemia

A
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14
Q

Describe the presentation of hypercalcemia

A
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15
Q

Describe the diagnostics for hypercalcemia

A
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16
Q

Describe the treatment for hypercalcemia

A
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17
Q

Describe the etiology of hyperparathyroidism

A
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18
Q

Describe the presentation of hyperparathyroidism

A
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19
Q

Describe the labs of hyperparathyroidism

A
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20
Q

Describe the treatment of hyperparathyroidism

A
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21
Q

Describe the etiology of hypoparathyroidism

A
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22
Q

Describe the presentation of hypoparathyroidism

A
23
Q

Describe the labs for hypoparathyroidism

A
24
Q

Describe the treatment for hypoparathyroidism

A
25
Q

Describe the etiology of pseudohypoparathyroidism

A
26
Q

Describe the presentation of pseudohypoparathyroidism

A
27
Q

Describe the labs for pseudohypoparathyroidism

A
28
Q

Describe the treatment for pseudohypoparathyroidism

A
29
Q

What is this called and what is it seen in

A

brachymetacarpals/tarsals seen in pseudohypoparathyroidism

30
Q

Describe the eitology of osteoporosis

A
31
Q

Describe the presentation of osteoporosis

A
32
Q

Describe the diagnosis of osteoporosis

A
33
Q

Describe the treatment of osteoporosis

A
34
Q

Describe the screening recommendations for osteoporosis

A
35
Q

Describe the etiology of vit D deficiency

A
36
Q

Describe the presentation of vit D deficiency

A
37
Q

Describe the labs for vit D deficiency

A
38
Q

Describe the treatment for vit D deficiency

A
39
Q

Describe the etiology of osteomalacia

A
40
Q

Describe the presentation of osteomalacia

A
41
Q

Describe the diagnosis of osteomalacia

A
42
Q

Describe the treatment for osteomalacia

A
43
Q

Describe the etiology of Rickets

A
44
Q

Describe the presentation of rickets

A
45
Q

Describe the diagnosis of rickets

A
46
Q

Describe the treatment of rickets

A
47
Q

Describe the etiology of paget’s disease of the bone

A
48
Q

Describe the presentation of paget’s disease of the bone

A
49
Q

Describe the labs for paget’s disease of the bone

A
50
Q

Describe the treatment for paget’s disease of the bone

A
51
Q

What is the most common cause of hypercalcemia

A

malignancy (breast, lung, renal, multiple myeloma)

52
Q

Describe the etiology of malignancy & hypercalcemia

A
  • tumor secretion of PTH related protein & production of calcitriol
53
Q

Describe the evaluation of malignancy & hypercalcemia

A

clinical hx

low/undetectable PTH, low vit D

Endocrine (10 decks)

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