Adrenal Disorders Flashcards

1
Q

What is the difference between a functional tumor & an adenoma

A

Functional tumors are hormone secreting & adenomas are benign

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2
Q

What are the 3 main substances secreted by the adrenal cortex

A
  • aldosterone (mineralcorticoid - granulosa)
  • cortisol (glucocorticoids - fasciculata)
  • androgens (reticularis)
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3
Q

What is the main substance secreted by the adrenal medulla

A

catecholamines (epi & norepi)

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4
Q

What is adrenal insufficiency

A

rare disorder that occurs when there is insufficient function of the adrenal cortex leading to underproduction of corticosteroids

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5
Q

What are the classifications of adrenal insufficiency

A
  • primary (Addison’s): dysfunction of the adrenal gland
  • secondary: deficiency of ACTH due to dysfunction of the pituitary gland
  • tertiary: deficiency of ACTH due to dysfunction of the hypothalamus
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6
Q

What happens when there is an increase in ACTH

A

glucocorticoids & androgens increaseW

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7
Q

Why doesn’t aldosterone increase when there is an increase in ACTH

A

regulation from the renin-angiotensin-aldosterone system

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8
Q

Describe the etiology of adrenal insufficiency & types

A
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9
Q

Describe the presentation of primary & secondary chronic adrenal insufficiency

A
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10
Q

Describe the etiology & presentation of acute adrenal crisis

A
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11
Q

Describe the testing for adrenal insufficiency

A
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12
Q

What are the common lab findings of adrenal insufficiency

A
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13
Q

Describe the treatment of chronic adrenal insufficiency

A
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14
Q

Describe the etiology of cushing’s syndrome

A
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15
Q

Describe etiology & presentation of pseudo-cushing’s syndrome

A
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16
Q

Describe the presentation of cushing’s syndrome

17
Q

Describe the treatment of cushing’s syndrome

18
Q

Describe the treatment of cushing’s disease

19
Q

Describe the etiology of pheochromocytoma

20
Q

Describe the presentation of pheochromocytoma

21
Q

Describe the workup for a pheochromocytoma

22
Q

Describe the treatment of a pheochromocytoma

23
Q

Describe the etiology of primary hyperaldosteronism

24
Q

Describe the presentation of primary hyperaldosteronism

25
Describe the workup for primary hyperaldosteronism
26
Describe the treatment for primary hyperaldosteronism
27
Describe the etiology of congenital adrenal hyperplasia
28
Describe the presentation of congenital adrenal hyperplasia & treatment
Tx with corticosteroid replacement
29
Describe the etiology of adrenal incidentaloma