Adrenal Disorders Flashcards
What is the difference between a functional tumor & an adenoma
Functional tumors are hormone secreting & adenomas are benign
What are the 3 main substances secreted by the adrenal cortex
- aldosterone (mineralcorticoid - granulosa)
- cortisol (glucocorticoids - fasciculata)
- androgens (reticularis)
What is the main substance secreted by the adrenal medulla
catecholamines (epi & norepi)
What is adrenal insufficiency
rare disorder that occurs when there is insufficient function of the adrenal cortex leading to underproduction of corticosteroids
What are the classifications of adrenal insufficiency
- primary (Addison’s): dysfunction of the adrenal gland
- secondary: deficiency of ACTH due to dysfunction of the pituitary gland
- tertiary: deficiency of ACTH due to dysfunction of the hypothalamus
What happens when there is an increase in ACTH
glucocorticoids & androgens increaseW
Why doesn’t aldosterone increase when there is an increase in ACTH
regulation from the renin-angiotensin-aldosterone system
Describe the etiology of adrenal insufficiency & types
Describe the presentation of primary & secondary chronic adrenal insufficiency
Describe the etiology & presentation of acute adrenal crisis
Describe the testing for adrenal insufficiency
What are the common lab findings of adrenal insufficiency
Describe the treatment of chronic adrenal insufficiency
Describe the etiology of cushing’s syndrome
Describe etiology & presentation of pseudo-cushing’s syndrome
Describe the presentation of cushing’s syndrome
Describe the treatment of cushing’s syndrome
Describe the treatment of cushing’s disease
Describe the etiology of pheochromocytoma
Describe the presentation of pheochromocytoma
Describe the workup for a pheochromocytoma
Describe the treatment of a pheochromocytoma
Describe the etiology of primary hyperaldosteronism
Describe the presentation of primary hyperaldosteronism
Describe the workup for primary hyperaldosteronism
Describe the treatment for primary hyperaldosteronism
Describe the etiology of congenital adrenal hyperplasia
Describe the presentation of congenital adrenal hyperplasia & treatment
Tx with corticosteroid replacement
Describe the etiology of adrenal incidentaloma
