Parasitology Flashcards

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1
Q

What is the definitive host in a parasitic infection?

A

The host where the parasite gains sexual maturity as well as reproducing inside of.

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2
Q

Wha is the intermediate host in a parasitic infection?

A

The host whereby the parasite develops and reproduces asexually

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3
Q

What is the paratenic host in a parasitic infection?

A

Not a part of the parasites life cycle but one that is used as a vehicle to get to the obligatory host

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4
Q

What is a protist?

A

referes to a single-celled colonial eukaryote other than fungi. Includes many diverse clades of algae and protozoa

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5
Q

What are protozoa?

A

Single celled heterotrophic protists

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6
Q

What are the features of protists?

A

flagella

undulating membrane

cysts- dormant stage w thick protective wall

kinetoplast- one large mitochondrion

pseudopods- projection of membrane and cytoplasm that allows movement and phagocytosis

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7
Q

Parasites -> protozoa –> Excavata

Within the excavata supergroup there metamonada and discicristata. What are the organisms/features associated with metamonada?

A

Giardia, trichomonas

Reduced mitochondria

pinocytosis

specialized structures used for species identification

intestinal parasites

form cysts

have cilia

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8
Q

Parasites -> protozoa –> Excavata

Within the excavata supergroup there metamonada and discicristata. What are the organisms/features associated with discicristata?

A

Naegleria, leishmania, trypanosoma

cytoskeleton

flat or disc shaped cristae in the mitochondria

can be free living or vector transmitted

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9
Q

Parasites -> protozoa –> Amoebozoa

Within the amoebozoa supergroup what are the organisms/features associated with it?

A

Acanthamoeba, balamuthia, entamoeba, endolimax, lodamoeba

Locomotion achieved by pseudopodia

Mitchondria with tubular cristae

Phagocytic

Form cysts

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10
Q

Parasites -> protozoa –> SAR

Within the SAR supergroup there apicomplexa (sporozoaans), Ciliophora, stramenopila. What are the organisms/features associated with apicomplexa?

A

Babesia, plasmodium, cryptosporidium, cyclosora, cystoisospora, sarcocystis, toxoplasma

-complex organelles in apical tip to penetrate host barriers

-adults have no cilia or flagella

-multiple forms

-pinocytosis

-alternate between sexual and asexual reproduction

-frequently intracellular

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11
Q

Parasites -> protozoa –> SAR

Within the SAR supergroup there apicomplexa (sporozoaans), Ciliophora, stramenopila. What are the organisms/features associated with ciliophora?

A

Balantidium coli

  • cilia = locomotion
  • only ciliate parasite in humans
  • has macro- and micronucleus
  • uses conjugation for sexual reproduction and binary fission for asexual reproduction
  • Nutrition via ingestion through cytosome
  • forms cysts
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12
Q

Of the parasitic worm family otherwise known as helminths, what are the distinguishing features of the Platyhelminths or “flatworms”?

A

Free living in water or damp soil

tissue acting like organs but no specialized respiratory, circulatory or digestrive tracts

gus is gastrovascular cavity –>ie single opening for intake and output

complex reproduction with many hermaphroditic species

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13
Q

Of the parasitic worm family otherwise known as helminths, what are the distinguishing features of the Trematodes or “flukes”?

A

complex life cycle with encysted egg stages and temporary larval forms

Multiple sucker devices => 1 for nutrition/waste and 1 for attachement

Will generally includea definitive host and intermediate host

When humans are the definitive hosts, fertilized eggs are excreted through feces and urine

-In water, eggs develop into ciliated larvae

–>Larvae then infect intermediate host (such as fish) to reproduce asexually and then escape to environment where they are picked up by the definitive host (human in this case)

—>evades host immunity by mimmicking host cell surface proteins

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14
Q

Of the parasitic worm family otherwise known as helminths, what are the distinguishing features of the Cestodes aka tapeworm?

A

infects all mammals and many other vertebrates

typically 2 hosts- hermaphroditic

most common source of human infection is the ingestion of cysts in undercooked meat

Live in intestines and can grow to meters in length

ribbon like body made of proglottids- reproductive units

–>once the proglottid/eggs are free they are able to spread through water

No GI tract absorb nutrition throughout their entire body

wasting disease => as worm load increases more nutrients are stolen from the host

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15
Q

Of the parasitic worm family otherwise known as helminths, what are the distinguishing features of the Nematode or roundworm?

A

Parasitize all plants and animals

mm to meters in length

covered in protective covering known as cuticle

have longitudinal muscles and separate sexes but no circulatory system

larvae resemble mini adults and grow via cell enlargement and mitosis

Wasting disease is what ultimately causes host damage via blockage

Cause nutritional deficiencies and muscle damage

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16
Q

What is the general parasite infection process?

A

exposure- parasites come from outside the body

entry- ingestion, insect vectors, or penetration

adherence- physically attaching to host niche

replication

tissue damage- by immune system usually not toxins

immune evasion- antigen variatio, molecular mimmickry, suppresion of host immune system, masking parasitic outer layers

17
Q

What are the 3 common parasite disease we need to know about for this class?

A
  1. Giardiasis

–>Giardia intestinalis

  1. Chagas disease (American trypanosomiasis)

–>trypanosomiasis cruzi

  1. Beef/pork tapeworm disease

–>Taenia saginata, T. solium