Parasitology Flashcards
Types of Protozoan present in the
INTESTINAL TRACT
Entamoeba histolytica –> Amebiasis
Giardia lamblia –> Giardiasis
Cryptosporidium parvum –> Cryptosporidiosis
Types of Protozoan present in the
UROGENITAL TRACT
Trichomonas vaginalis –> Trichomoniasis
Types of Protozoan present in the
BLOOD AND TISSUE
Plasmodium spp. –> Malaria
Taxoplasma gondii –> Taxoplasmosis
Trypanosoma spp. –> Chagas disease, sleeping sickness
Fruits of Pathology:
strawberry
cervix –> trichomoniasis
tongue –> TSS, kawasaki, SF
gallbladder –> cholesterolosis
Fruits of Pathology:
berry
aneurysms –> SAH, ADPKD, coarctation of aorta
Fruits of Pathology:
mulberry
molars –> congenital syphilis
tumor –> tuberous sclerosis
Fruits of Pathology:
blueberry
muffin baby –> congenital rubella, congenital CMV
Fruits of Pathology:
grape-like
vesicles –> hydatidiform mole
clusters –> S. aureus
bunches –> sarcoma botryoides
odor –> P. aeruginosa
Fruits of Pathology:
cherry-red
epiglottis –> epiglottitis
spot in macula –> CRAO, Tay-sachs, Niemann-pick
pigment –> S. marcescens
skin –> CO poisoning
Fruits of Pathology:
banana-shaped
gametocytes –> P. falciparum
left ventricle –> hypertrophic cardiomyopathy
Fruits of Pathology:
orange
peel skin –> inflammatory breast CA
cast skin –> leptospirosis
colonies –> N. asteroides
Fruits of Pathology:
pear-shaped
trophozoites –> Trichomonas, Giardia
organ –> prostate gland
Malaria specie comparison in terms of
Asexual cycle
P. falciparum: 48 hours
P. vivax: 48 hours
P. malariae: 72 hours
P. ovale: 48 hours
Malaria specie comparison in terms of
Periodicity
P. falciparum: Malignant tertian
P. vivax: Benign tertian
P. malariae: Benign quartan
P. ovale: Benign tertian
Malaria specie comparison in terms of
RBC preference
P. falciparum: All ages
P. vivax: young RBCs
P. malariae: Old RBCs
P. ovale: young RBCs
Malaria specie comparison in terms of
Parasitemia
P. falciparum: Highest
P. vivax: Low
P. malariae: Lowest
P. ovale: Low
Malaria specie comparison in terms of
Merozoites
P. falciparum: 0
P. vivax: 12-24
P. malariae: 6-12
P. ovale: 8
Malaria specie comparison in terms of
Gametocytes
P. falciparum: Banana-shaped
P. vivax: Large round
P. malariae: Compact
P. ovale: Small round
Malaria specie comparison in terms of
Cerebral malaria
P. falciparum: Yes
P. vivax: No
P. malariae: No
P. ovale: No
Malaria specie comparison in terms of
Recrudescence
P. falciparum: Yes
P. vivax: No
P. malariae: Yes
P. ovale: No
Malaria specie comparison in terms of
Relapse
P. falciparum: No
P. vivax: Yes
P. malariae: No
P. ovale: yes
Malaria specie comparison in terms of
Drug resistance
P. falciparum: Many
P. vivax: Few
P. malariae: Few
P. ovale: Few
Mnemonic-Malarial Dots
Schuffner dots = P.Ovale & Vivax
SOVrang daming dots!
Maurer dots = coMMa-shaped = P. falciparuM
Treatment
Chloroquine-sensitive P. falciparum and P. malariae infections
Chloroquine
Treatment
P. vivax and P ovale infections
Chloroquine + Primaquine
Treatment
Uncomplicated infections with chloroquine -resistant P. falciparum
Drug Therapy: Quinine + Doxycycline / Clindamycin Alternative Drug: Malarone (Atavaquone-Proguanil) OR Mefloquine OR Co-Artemether + Lumefantrine
Treatment
Severe or complicated infections with P. falciparum
Drug Therapy: Artesunate + Doxycycline / Clindamycin OR Mefloquine / Malarone OR Alternative Drug: Quinidine gluconate Artemether + Doxycycline / Clindamycin OR Mefloquine / Malarone
Mnemonic-Malarial Dots
Schuffner dots = P.Ovale & Vivax
SOVrang daming dots!
Maurer dots = coMMa-shaped = P. falciparuM
Treatment
Chloroquine-sensitive P. falciparum and P. malariae infections
Chloroquine
Treatment
P. vivax and P ovale infections
Chloroquine + Primaquine
Treatment
Uncomplicated infections with chloroquine -resistant P. falciparum
Drug Therapy: Quinine + Doxycycline / Clindamycin Alternative Drug: Malarone (Atavaquone-Proguanil) OR Mefloquine OR Co-Artemether + Lumefantrine
Treatment
Severe or complicated infections with P. falciparum
Drug Therapy: Artesunate + Doxycycline / Clindamycin OR Mefloquine / Malarone OR Alternative Drug: Quinidine gluconate Artemether + Doxycycline / Clindamycin OR Mefloquine / Malarone
Prophylactic Treatment for areas without resistant P. falciparum
Chloroquine
Prophylactic Treatment for areas with chloroquine-resistant P. falciparum
Malarone / Mefloquine
Prophylactic Treatment for areas with multidrug-resistant P. falciparum
Doxycycline
Prophylactic Treatment for Terminal prophylaxis of P.vivax and P.ovale infections; alternative for primary prevention
Primaquine
Mnemonic-Sleeping Sickness
Think WaGER
West = Gambian –> Western Gate
East = Rhodesian –> Eastern Road
Mnemonic-Treatment of Sleeping Sickness
It SURe is nice to go to SLEEP. MELAtonin helps with SLEEP.
SURAmin-MELArsoprol is used for African SLEEPing sickness.
What is responsible for patients with facial paresthesia, total paralysis, respiratory failure?
Syndrome: Paralytic
Toxin: Saxitoxin
Incubation: 15mins
What is responsible for patients with facial paresthesia, slurred speech, ataxia, diarrhea?
Syndrome: Neurotoxic
Toxin: Brevetoxin
Incubation: 15mins
What is responsible for patients with diarrhea, nausea and vomiting, abdominal pain?
Syndrome: Diarrhetic
Toxin: Okadaic acid
Incubation: 30mins
What is responsible for patients with diarrhea, short-term memory loss, seizures?
Syndrome: Amnesic
Toxin: Domoic acid
Incubation: 30mins
T. Solium Transmission: Intermediate Host: Site Affected: Treatment:
Transmission: eggs / larvae in undercooked pork
Intermediate Host: Pigs
Site Affected: Intestine
Treatment: Praziquantel
T. Saginata Transmission: Intermediate Host: Site Affected: Treatment:
Transmission: in uncooked beef
Intermediate Host: Cattle
Site Affected: Intestine
Treatment: Praziquantel
D. Latum Transmission: Intermediate Host: Site Affected: Treatment:
Transmission: arvae in uncooked fish
Intermediate Host: Fish
Site Affected: Intestine
Treatment: Praziquantel
E. Granulosus Transmission: Intermediate Host: Site Affected: Treatment:
Transmission: eggs in food contaminated with dog feces
Intermediate Host: Sheep
Site Affected: Liver
Treatment: Albendazole
S. japonicum Transmission: Sites Affected: Intermediate Hosts: Treatment:
Transmission: Penetrate skin
Sites Affected: Liver
Intermediate Hosts: Snail
Treatment: Praziquantel
P. westermani Transmission: Sites Affected: Intermediate Hosts: Treatment:
Transmission: Ingested with raw crab
Sites Affected: Lung
Intermediate Hosts: Snail and crab
Treatment: Praziquantel
C. sinensis Transmission: Sites Affected: Intermediate Hosts: Treatment:
Transmission: Ingested with raw fish
Sites Affected: Liver
Intermediate Hosts: Snail and fish
Treatment:Praziquantel
NEMATODES Species Ascaris Location: Disease: Transmission: Treatment:
Location: Intestines
Disease: Ascariasis
Transmission: Ingestion of eggs
Treatment: Albendazole
NEMATODES Species Ancylostoma and Necator Location: Disease: Transmission: Treatment:
Location: Intestines
Disease: Hookworm
Transmission: Larval penetration of skin
Treatment: Albendazole
NEMATODES Species Trichuris Location: Disease: Transmission: Treatment:
Location: Intestines
Disease: Whipworm
Transmission:Ingestion of eggs
Treatment: Mebendazole
NEMATODES Species Enterobius Location: Disease: Transmission: Treatment:
Location: Intestines
Disease: Pinworm
Transmission: Ingestion of eggs
Treatment: Pyrantel pamoate
NEMATODES Species Strongyloides Location: Disease: Transmission: Treatment:
Location: Intestines
Disease: Stronggyloidiasis
Transmission: Larval penetration of skin
Treatment: Ivermectin
NEMATODES Species Capillaria Location: Disease: Transmission: Treatment:
Location: Intestines
Disease: Capillariasis
Transmission: eggs in undercooked fish
Treatment: Albendazole
NEMATODES Species Wuchereria and Brugia Location: Disease: Transmission: Treatment:
Location: Tissue
Disease: Filariasis
Transmission: Mosquito bite
Treatment: DEC
NEMATODES Species Trichinella Location: Disease: Transmission: Treatment:
Location: Tissue
Disease: Trichinosis
Transmission: Larvae in uncooked meat
Treatment: Thiabendazole
Wuchereria VS Brugia
Appearance
Wuchereria: Smoothly curved
Brugia: Kinky
Wuchereria VS Brugia
Terminal Nuclei
Wuchereria: Absent
Brugia: Present
Wuchereria VS Brugia
Prevalence
Wuchereria: Widespread
Brugia: SEA only
Wuchereria VS Brugia
Mosquito vectors
Wuchereria: Culex, Aedes, Anopheles
Brugia: Mansonia
Wuchereria VS Brugia
Preference
Wuchereria: Scrotal lymphatics
Brugia: Limb lymphatics
Wuchereria VS Brugia
Clinical Picture
Wuchereria: Hydrocoele
Brugia: Elephantiasis
Wuchereria VS Brugia
Severity
Wuchereria: More severe
Brugia: Less severe
What causes Pruritis of scalf or trunk; nits seen on hair shaft?
Lice
Pediculus humanus
What causes Pruritis in pubic area; nits seen on hair shaft?
Lice
Phthirus pubis
What causes Pruritic, painful, and erythematous nodule; larva may be seen emerging from nodule
Flies
Dermatobia hominis
What causes Pruritic, erythematous wheal?
Bedbugs
Cimex lectularius
What causes Pruritic, erythematous papules, and linear tracks?
Mites
Sarcoptes scabei
What causes Ascending paralysis?
Ticks
Dermacentor