Paraneoplastic Syndromes Flashcards
1
Q
What paraneoplastic syndrome occurs in small cell lung cancer?
A
Cushing: tumor makes ACTH/ACTH-like peptide
SIADH: tumor makes ADH
Lambert-Eaton: tumor makes autoAb to NMJ ca++ channels
2
Q
What paraneoplastic syndrome occurs in SCC of lung?
A
Hypercalcemia: makes PTHrP
3
Q
What paraneoplastic syndrome occurs in renal cell cancer?
A
Hypercalcemia: makes PTHrP
Polycythemia: Makes EPO
4
Q
What paraneoplastic syndrome occurs in breast cancer?
A
Hypercalcemia: makes PTHrP
5
Q
What syndrome occurs in Hodgkin’s lymphoma
A
Hypercalcemia: makes 1, 25-(OH)2 Vitamin D
6
Q
What cancers make EPO?
A
Renal cell
Hemangioblastoma
HCC
Pheo