Oncogenic Micro and Chemicals

Question 1

What does HTLV-1 cause?

Answer 1

Adult T-cell leukemia/lymphoma

Question 2

What does EBV cause?

Answer 2

Burkitt’s lymphoma
Hodgekin’s lymphoma
Nasopharyngeal carcinoma
CNS lymphoma

Question 3

What does HCV cause?

Answer 3

HCC

Question 4

What does HBV cause?

Answer 4

HCC

Question 5

What does HPV cause?

Answer 5

Cervical cancer (esp. 16, 18)
Penile, anal cancer
Upper Resp SCC

Question 6

What does HHV-8 cause?

Answer 6

Kaposi’a

Question 7

What does H. pylori cause?

Answer 7

Gastric adenocarcinoma and lymphoma

Question 8

What does Schistosoma haematobium cause?

Answer 8

Baldder cancer (SCC)

Question 9

What does Liver fluke cause?

Answer 9

Cholangiocarcinoma

Question 10

What do aflotoxins cause?

Answer 10

HCC

Question 11

What organism makes aflotoxins? What dz can this cause?

Answer 11

Aspergillus

HCC

Question 12

What does vinyl chloride cause?

Answer 12

Angiosarcoma

Question 13

What does CCl4 cause?

Answer 13

Centrilobular liver necrosis and fatty change

Question 14

What does nitrosamines cause? Where are they found?

Answer 14

Gastric cancer

Smoked foods (think Japan/Asia)

Question 15

What does Cigarette smoke cause?

Answer 15

SCC of resp. tract
Lung cancer
Kidney and bladder cancer
Pancreatic cancer

Question 16

What does Asbestos cause?

Answer 16

Mesothelioma

Question 17

What does Arsenic cause?

Answer 17

SCC of skin

Angiosarcoma of liver

Question 18

What does Naphthalene (anilene dye) cause?

Answer 18

Transitional cell cancer os bladder

Question 19

What do alkylating agents cause?

Answer 19

Leukemia