Paraneoplastic syndromes Flashcards
Cushing syndrome
small cell carcinoma of the lung
pancreatic carcinoma
neural tumors
caused by secretion of ACTH or like substance
inappropriate anti-diuretic hormone
small cell carcinoma of the lung
intracranial neoplasms
caused by anti-diuretic hormone or
atrial natriuretic hormones
hypercalcemia
squamous cell carcinoma of the lung
breast carcinoma, renal carcinoma,
Adult T-cell leukemia/lymphoma
caused by Parathyroid hormone-related protein (PTHRP)
TGF-alpha, TNF, IL-1
Hypoglycemia
Ovarian carcinoma, Fibrosarcoma,
other mesenchymal sarcomas
caused by insulin or insulin like substance
Carcinoid syndrome
hepatocellular carcinoma
bronchial adenoma
pancreatic carcinoma
caused by serotonin, bradykinin
Polycythemia
gastric carcinoma
renal carcinoma
cerebellar hemangioma
hepatocellular carcinoma
caused by eythropoietin
Myasthenia
bronchogenic carcinoma
caused by immunological processes
Disorders of CNS & PNS
Breast carcinoma
caused by immunological processes
Acanthosis Nigricans
Gastric carcinoma
lung carcinoma
uterine carcinoma
Caused by secretion of epidermal growth factor
Dermatomyositis
bronchogenic,
breast carcinoma
caused by immunological processes
Hypertrophic osteoarthropathy & clubbing of the fingers
bronchogenic carcinoma
Venous thrombosis
(Trousseau phenomenon)
pancreatic carcinoma
bronchogenic carcinoma
other cancers
casued by tumor produced mucins that activate clotting
Nonbacterial thrombotic endocarditis
advanced cancers
hypercoagulability
red cell aplasia
thymic neoplasms
Nephrotic syndrome
various cancers
caused by tumor antigens, immune complexes
