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Pathology > Paraneoplastic effects of tumors > Flashcards

Paraneoplastic effects of tumors Flashcards

Hormone/agent, Effect, Neoplasm

1
Q

ACTH or ACTH-like peptide

A

Cushing’s syncrome

Small cell lung carcinoma

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2
Q

ADH

A

SIADH

Small cell lung carcinoma and intracranial neoplasms

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3
Q

PTH-related peptide, TGF-beta, TNF, IL-1

A

Hypercalcemia

Squamous cell lung carcinoma, renal cell carcinoma, and breast carcinoma

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4
Q

Erythropoietin

A

Polycythemia

Renal cell carcinoma, hemangioblastoma, hepatocellular carcinoma, pheochromocytoma

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5
Q

Antibodies against presynaptic Ca2+ channels at neuromuscular junction

A

Lambert-Eaton syndrome (muscle weakness)

Thymoma, small cell lung carcinoma

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6
Q

Hyperuricemia due to excess nucleic acid turnover

A

i.e., cytotoxic therapy

Gout, urate nephropathy

Leukemias and lymphomas

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Pathology (6 decks)

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