Chemical carcinogens: Toxin, organ, and impact Flashcards
1
Q
Aflatoxins
A
Aflatoxins (Aspergillus)
Liver
Hepatocellular carcinoma
2
Q
Vinyl chloride
A
Liver
Angiosarcoma
3
Q
CCl4
A
Liver
Centrilobular necrosis, fatty change
4
Q
Nitrosamines
A
Nitrosamines = smoked foods
Stomach
Gastric cancer
5
Q
Cigarette smoke
A
Larynx, Lung, Kidney, Bladder
Larynx- Squamous cell carcinoma
Lung- Squamous cell and small cell carcinoma
Kidney- Renal cell carcinoma
Bladder- Transitional cell carcinoma
6
Q
Asbestos
A
Lung
Mesothelioma and bronchogenic carcinoma
7
Q
Arsenic
A
Skin, Liver
Skin- Squamous cell carcinoma
Liver- Angiosarcoma
8
Q
Napthalene dyes
A
Napthalene = aniline
Bladder
Transitional cell carcinoma
9
Q
Alkylating agents
A
Blood
Leukemia