Chemical carcinogens: Toxin, organ, and impact Flashcards

1
Q

Aflatoxins

A

Aflatoxins (Aspergillus)

Liver

Hepatocellular carcinoma

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2
Q

Vinyl chloride

A

Liver

Angiosarcoma

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3
Q

CCl4

A

Liver

Centrilobular necrosis, fatty change

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4
Q

Nitrosamines

A

Nitrosamines = smoked foods

Stomach

Gastric cancer

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5
Q

Cigarette smoke

A

Larynx, Lung, Kidney, Bladder

Larynx- Squamous cell carcinoma
Lung- Squamous cell and small cell carcinoma
Kidney- Renal cell carcinoma
Bladder- Transitional cell carcinoma

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6
Q

Asbestos

A

Lung

Mesothelioma and bronchogenic carcinoma

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7
Q

Arsenic

A

Skin, Liver

Skin- Squamous cell carcinoma
Liver- Angiosarcoma

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8
Q

Napthalene dyes

A

Napthalene = aniline

Bladder

Transitional cell carcinoma

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9
Q

Alkylating agents

A

Blood

Leukemia

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