Paramyxoviridae until Arboviridae Flashcards
This virus spreads through direct person to person contact
parainfluenza
The envelope of the virus paramyxoviridae consists of
Viral Hemagglutinin
This virus is common among chicken or older birds
Newcastle Disease Virus
What are the common clinical manifestation of parainfluenza
Common colds, croup (laryngotracheobronchitis), pneumonia, and bronchiolitis
The only clinical manifestation of this virus in humans is the conjunctiva
Newcastle Disease Virus
Also known as the conjunctiva
sore eyes
This is the most important pathogen in the lower respiratory tract in infants
Respiratory Syncytial Virus (RSV)
RSV is trasmitted via
large droplets and fomites
Difference of paramyxoviridae from orthomyxoviridae
The peplomer of paramyxoviridae has both neuraminidase and hemagglutinin while in orthomyxoviridae we find neuraminidase and hemagglutinin in separate peplomer.
True or False
paramyxoviridae are more antigenically stable
True
This infection is particularly serious in children
Parainfluenza
Newcastle disease can cause ________ in young chickens
Pneumoencephalitis
What are the clinical manifestation of RSV
Common colds, febrile bronchitis, pneumonia, bronchiolitis, and otitis media
If laboratory grown RSV, the expected clinical manifestation would be?
Syncytia
This infection is relatively common on school-age children
Mumps
Common clinical manifestation of mumps is?
Painful inflammation of parotid salivary glands
What vaccine is used for mumps
MMR (measles mumps rubella) vaccine
It is also known as red measles
Rubeola
What is the main manifestation of rubeola?
Rash and fever
It is the bluish white ulcerations on the buccal mucosa
Koplik’s Spots (pathognomonic)
Subacute sclerosing panecephalitis is a result of severe?
Rubeola infection
Demyelinating disorder of the nervous system
Guillain-Barre Syndrome
This virus produces respiratory tract infections that are similar to RSV
Human Metapneumovirus
This is often a result of a previous viral infections
Guillain-Barré Syndrome
What happens to the body of the patient if the person acquired Guillain-Barré syndrome?
The hosts immune system destroyed its own nerves or myelin covering of the nerves.
Rubella is also known as
3 day measles or German measles
Rubella is under what family?
Togaviridae
Mildest form of common exanthem
Rubella
Most common transmission of rubella virus
Respiratory
In rubella virus, the infected mother can pass the infection to the fetus. This process is called?
Congenital Transmission
Incubation period of mumps
7-25 days
Severe mumps can lead to the what infections?
Parotitis, aseptic meningitis, and meningoencephalitis.
True or False
All mumps infection is characterized by the inflammation of parotid glands
False. Not all mumps infection leads to inflammation of parotid glands
Organs that can be affected if patient has mumps
Testes, pancreas, ovaries, and the CNS
True or False
When a patient gets infected with rubeola and mumps, after infection they acquire lifelong immunity.
True
Severe rubeola can lead to?
Secondary bacterial infection, Giant cell pneumonia, acute encephalitis, and subacute sclerosing panecephalitis.
In Nipah virus, what animal is considered as natural reservoirs?
Bats
Human may be infected by this virus by resulting from contact with infected horses
Hendra Virus
All cases of Hendra Virus are confined in?
North-East coast of Australia
This virus can be acquired through pig-to-human or human-to-human contact
Nipah Virus
Incubation period of rubeola virus
9-11 days
It is the least performed and least practical viral detection
Viral isolation or culture
It is the gold standard for detecting viral infection
Viral isolation
Why is viral isolation not practical?
Because of the long turn around time and it needs a highly skilled and trained laboratory personnel
This viral detection is currently considered as the best method for case detection
Nucleic Acid Amplification
It is a test that is highly sensitive and has very high specificity
Nucleic acid amplification
It is a test that is not reliable for current cases
Antibody detection
What test is used to check past infections
Antibody detection
What viral detection is the most expensive?
Viral isolation
It is a test that most likely to produce false-positive results
Nucleic acid amplification
This viral detection test is commonly used today but is not as sensitive as nucleic acid detection
Antigen Detection
This test most likely to produce false negative results
Antigen Detection
This detects the presence of viral genome but it does not necessarily mean that the patient has infective virus particles
Nucleic acid amplification
Its progeny matures by budding through the endoplasmic reticulum and golgi
Coronaviridae
