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MSK 2 Final DF > papulosquamous and vesiculobullous diseases Matthys > Flashcards

papulosquamous and vesiculobullous diseases Matthys Flashcards

1
Q

scaring atrophic photosensitizing dermatosis
mild itching
SCC transformation can occur in chronic lesions
hypo or hyper pigment
erythematous papule or plaque with modes amt of scale
mucosal, palms, and soles

A

discouid lupus erythematosus

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2
Q

push on this and feels like it pushes back

A

bullous pemphigoid

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3
Q

branny greasy red scale on face/chest/penis
mild flaking in hair baring areas
sebopsoriasis

A

seborrheic dermatitis

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4
Q

who has a 10X increase in drug eruption incidence

A

immunocompromised

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5
Q

causes/clinical psoriasis vulgaris

A

trauma
infection: HIV
sunlight/ drugs lithium b blocker nsaids

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6
Q

diagnosis and treament of dermatitis herpetiformis

A

HE and DIF biopsy

gluten free diet

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7
Q

DD erythrasma

A

tinea

psoriasis

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8
Q

treatment of EM

A

antivirals

steroids

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9
Q

erythrasma bacteria, climate, disesae

A

corynebacterium minutissimum
chronic
diabetes
warm humid places

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10
Q

staph scalded skin syndrome

A

sever impetigo to widespread skin denudation
exfoliation then painful erythema
**blister at the granular layer of the epidermis splitting desmosomes (TEN doesn’t have this)

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11
Q

treatmetn for impetigo and can possibly get

A

Antibiotics

glomerulonephritis

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12
Q

treatment for CTCL

A

topical steroids, PUVA, topical nitrogen mustard

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13
Q

DD herpes below belt, above belt

A

chancroid and urethritis

hand foot and mout disease
proctitis

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14
Q

reddish orange scaling plaaues of unknown etiology with palmoplantar keratoderma and follicular keratotic papules
thick palm and soles

A

pityriasis rubra pilaris

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15
Q

DD of TEN

A 
EM
scarlet fever
GVHD
SSSS
exfoliative dermatitis
generaized bullous fixed drug eruption
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16
Q

common site discoid lupus in african americans

A

ear

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17
Q

clinical TEN

A 
1-3 week prodrome
fever, skin tender
pain buring skin
new added drugs common
skin with crinkled surface
mucosal membrane involvement***
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18
Q

differential of SSS

A 
scarlet fever
kawasaki 
TEN
EM
child abuse
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19
Q

chicken pox spares

A

distal extremity

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20
Q

what involvement 70% of time in erythema multiforme

A

mucosal

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21
Q

pityriasis rosea

A

rose or pink colored scaly pathces or thin plaques

viral exanthem
CD4 and langerhan’s cells in dermis

“christmas tree”

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22
Q

tinea corporis

A 
superficial infection of skin
koh 
culture
skin, hair, nail
common under prostetics
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23
Q

wickham’s stria

A

lichen planus

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24
Q

diagnosis of CTCL

A

bioposy, chest xray cbc with buffy coat

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25
Q

dermatitis herpetiformis clinical
pruritic burning skin blister in symmetric fashion, grouped
urticarial wheal to vesicle to bulla
waxes and wanes

A

dermatitis herpetiformis clinical

26
Q

bullous pemphigoid clinical

A

formation of tense bulla
uv radiation or drug induced
bullous, vesicular, urticarial, acral in children

27
Q

pemphigus vulgaris
__ disorder of ___ and ___
circulating __

A

autoimmune disorder skin and oral mucosa

circulating IGG1 and 4

28
Q

treatment pityrisasis rubra pilaris

A

retinoids

29
Q

fever, faint orange red macules
positive nikolsky sign
paper like wrinkling of epidermis

A

staph scalded skin syndrome

30
Q

lichen planus and what disease

A

hepatitis C

31
Q

extensive full thickness skin detachment

A

Toxic epidermal necrolysis

32
Q

discoid lupus treatment and diagnosis

A

ana and biopsy
sunscreen
topical steroid
antimalerials

33
Q

scarring plaque on cheek

A

discoid lupus

34
Q

treatment of bullous pemph

A

prednisone

35
Q

treatment of pemphigus vulgaris

A

prednisone

imuran

36
Q

differential of impetigo

A 
herpes 
tinea pedis
bullous pemphigoid
staph scalded skin
pemphigus vulgaris
37
Q

staph scalded skin heals when

A

5-7 days

38
Q

treatment SSS

A

antibiotics

fluids

39
Q

polymorphous light eruption

A

idiopathic photodermatoses relating to sun exposure
papules, vesicles, plaques
mainly am indians
shows up 30 min after sun exposure

40
Q

clinical pemphigus vulgaris

A

mucosa then skin

flaccid bulla on skin with erosion in oral mucosa

41
Q

treatment drug eruption

A

antihistamines

steroids

42
Q

drug eruption

A

2 weeks after new meds

morbilliform, erythematous, macular papular eruption with minimal scale often

43
Q

pathophys of psoriasis vulgaris

A

immune based
smoking, sun, alcohol
HLA B-13
AD

44
Q

HSV 1 pathophysiology

A

respiratory droplets

45
Q

treatment erythrasma

A

antibioticl

46
Q

treatment of TEN

A 
iv fluid
burn unit
steroids as last resort
ivig 
prevent infection
47
Q

honey colored crusted regions

A

impetigo

48
Q

description of herpes

A

vesicle on top of erythematous base

49
Q

bullous pemphigoid

A

autoimmune subepidermal blister rarely involves oral mucosa

auto IgG against BPAG

50
Q

pathophys of erythema multiforme

A

drugs
infection
allergies to sun, food, etc

51
Q

oval teardrop on erythematous base

dew drop on rose pedal

A

chicken pox

varicella virus

52
Q

polymorphous light eruption treatment and diagnosis

A

topical steroid, oral or IM steroids, antimalerials
R/O porphyria, lupus
photopatch test

53
Q

scalp/face/chest
p ovale (abnormal immune response with normal amt of yeast)
humidity, trauma, seasons
hiv

A

seborrheic dermatitis

54
Q

s aureus, nares mainly, normal flora, neonates and infants most common for bullous

rapid blister, asymptomatic
hot weather
scratch then get

A

impetigo

55
Q

red brown scaly macules with erosive collarette like scale

wood’s lamp

A

erythrasma

56
Q

treat chicken pox

A

VZIG
antiviral
antihistamines

57
Q

scaling plaques which mimic eczema
itchy
multiple diff shades of red brown
round, oval annular or bizarre shape

A

CTCL

58
Q

benign self limited eruption classically seen as targetoid or iris shaped macules or vesiculopapules on palms or soles

A

erythema multiforme

59
Q

chronic inflammatory scaling eruption
more common in norway
pustular and erythroodermic flares
10% will suffer with psoriatic arthritis

A

psoriasis vulgaris

60
Q

DD pityrisasis rosea

A

2ndary syphillis

MSK 2 Final DF (10 decks)

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