laboratory testing in rheumatic diseases Johnston Flashcards
rim pattern
anti DS DNA
arthritis- bowel
IBD
UC
crohn’s more seen in this
behcets: ulcers in genital area, oral cavity, associated with arth too
reactive arth
-bowel infection
uric acid hyperuricemia
uric acid over 6.8
acute onset often 1st MTP
joints are hot, swollen, tedner, dusky, red
tophi in skin
arthritis endocrine
diabetes
-charcot joints, bony desruction of jt that cant feel pain bc of nerve damage
cheiroarthropathy- thick skin and stiff extreemity
thyroid- carpal/tarsal tunel syndrome
hyper PTH
acromegally
enthesopathy
inflammation of ligaments and tendons as insert into bony attachment, reactive arth
drugs that can cause lupus
SHIPP
sulfanomides hydralazine isoniazid phenytoin procainamide
CT is best for
bony abnormalities, erosions, fractures, degen or inflamm arthritis
pitting nails seen in
psoriatic arthritis
joint fluid analysis aspiration
normal fluid
non inflammatory
inflammatory
normal under 200
non inflam
200-2000
inflammatory states
2-50K
>50k is septic
boutonniere deform
RA
hyperflex of PIP
criteria for SLE
malar rash discoid rash photosensitivity oral ulcers arthritis serositis renal neurologic hematologic
arthritis seen in syndromes involving what organs
skin bowel lung endocrine eyes
Positive RF value >___ by ELISA or > ____ by latex fixation
45 for elisa
1:80 for latex fixation
oligo arthritis
3 or less joints involved
arthritis- pulmonary
hypertrophic pulmonary oesteoarthritis-- clubing nodules effusion hilar nodes infiltrates
anticentromere antibody in
scleroderma
CREST and progressive systemic sclerosis
RF found in what diseases rather than RA
sjogren cryoglobulinemia primary biliary cirrhosis MCT endocarditis sLE sarcoid, malignancy
chronic management gouty arthritis
xanthine oxidase inhitor
probenecid
MRI
useful for soft tissue abnormalties
-spine, SI, synovitis, tenosynovitis, erosions
IV gadolinium can cause nephrogenic systemic fibrosis in pts with kidney disease
pauci arthritis
5 or more involved
which imaging for RA
digital radiography
ultrasound for joint
ASO and anti DNAse B titers
evidence of preceding group A strep
acute RF
strep may cause arthritis
JONES criteria
poly arth
more than 6
treatment for acute gouty arthritis
NSAIDS
colchicine
steroids
