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Biochemistry > Paper 2 , One Words > Flashcards

Paper 2 , One Words Flashcards

1
Q

Ames test

A

Detect mutagenicity

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2
Q

Zinc dependent enzymes

A

Carbonic anhydride
Carboxypeptidase
Alkalin phosphatase

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3
Q

Applications of pcr

A

Diagnosis of bact and viral diseases
Medicolegal
Genetic disorders detection
Prenatal diagnosis of inherited
Cancer
Fossil

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4
Q

Klenow fragment

A

DNA Poly -I without 5’ -3’ exonuclease domain

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5
Q

Korenberg enzyme

A

DNA Polymerase I

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6
Q

Prostate cancer tumour marker

A

PSA
ACP
GGT

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7
Q

Gene therapy vectors

A

Retroviruses
Adenoviruses
Herpes simplex viruses
Adeno associated renal virus vectors

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8
Q

Frame shift mutations

A

Thalassemia
Premature chain termination
Run -on polypeptide

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9
Q

Xeroderma pigmentosa

A

Nucleotide excision repair disorder
Defective formation of thymidine divers

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10
Q

Type of collagen in connective tissues including bones

A

Type I

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11
Q

Inhibitor of both prokaryotic and eukaryotic translation

A

Puromycin

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12
Q

Epstein Barr Virus

A

Nasopharyngeal carcinoma
Burkitts lymphoma

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13
Q

Onco suppressor gene in the short arm of chromosome 17

A

P53

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14
Q

RNAP 2 is inhibited by

A

alpha amanitin

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15
Q

In ECF the most important buffer is

A

Bicarbonates

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16
Q

Most important buffer in intercellular fluid

A

Phosphate

17
Q

Bromosulphthalein BSP due to assess

A

Excretory function of liver

18
Q

Serum calcitonin marker for

A

Medullary carcinoma of thyroid gland

19
Q

Radio iodine uptake studies uses what

A

I-131

20
Q

Presence of urobilinogen in urine represents

A

Haemolytic jaundice

21
Q

Chain breaking anti oxidants

A

SOD
Uric acid
VIT c

22
Q

Basement membrane with connective tissue

A

Type IV

23
Q

Type 1 collagen

A

connective tissue including bones

24
Q

Type 7 collagen

A

Anchoring fibrils

25
Q

Serum level of sodium

A

135-145 mol/L

26
Q

Potassium level in serum

A

3.5 - 5.0 mmol/l

27
Q

Gratuitous inducer

A

Isopropyl thiogalactoside

28
Q

De Ritis ratio

A

AST /ALT

29
Q

Rf value

A

Distance travelled by the solute / distance travelled by the solvent

30
Q

Bence Jones proteins

A

Monoclonal light chains produced by plasmacytoma

31
Q

Storage form of iron

A

Ferritin binds to ferric ions

32
Q

Transport form of iron

A

Transferrin

33
Q

Oncogenes

A

ras
src
sis

34
Q

Oncosuppressor genes

A

Retinoblastoma RB
Wilms tumour WT
Familal adenomatous polyposis FAP
deleted in colon cancer DCC

35
Q

Drug used for post menopausal breast cancer

A

Tamoxifen

36
Q

Enzymes used as labels in ELISA

A

Alkaline phosphatase
Horseradish peroxidase

Biochemistry (10 decks)

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