1

Question 1

Glucose tolerance

Answer 1

ability to regulate the blood glucose conc after the administration of a test dose of glucose (1g/kg body weight)

Question 2

Insulin dependent diabetes mellitus

Answer 2

type 1

Question 3

NIDDM (type 2)

Answer 3

reduced sensitivity of tissues to insulin action

Question 4

low carbohydrate diet , gluconeogenesis from

Answer 4

amino acids

Question 5

low carbohydrate diet associated high ATP cost met by

Answer 5

oxidation of fatty acids

Question 6

what is gluconeogenesis

Answer 6

process of synthesising glucose or glycogen from noncarbohydrate

Question 6

T

Answer 6

T

Question 7

glycemic index definition

Answer 7

the increase in blood glucose after a test dose of carbohydrate compares with that after an equivalent amount of glucose

Question 8

low glycemic index foods are beneficial because

Answer 8

less fluctuation in insulin secretion

Question 9

molecular basis of sickle cell anemia

Answer 9

single base change / one part in 3 x 10^9

Question 10

second major intrinsic cause of hemolysis

Answer 10

hemoglobinopathies

Question 11

synthesis of glycine

Answer 11

catalyzed by - glycine aminotransferase
from - glyoxylate and glutamate/alanine
additional - from choline or serine

Question 12

breakdown of palmitic acid C16 requires

Answer 12

7 cycles of beta-oxidation —–> each producing 1 FADH2 and 1NADH molecule —– result in formation of eight 2C acetyl CoA molecules

Question 13

niacin can be synthesized from

Answer 13

tryptophan

Question 14

pellagra caused by deficiency of

Answer 14

tryptophan , niacin

Question 15

electron acceptor for isocitrate dehydrogenase,alpha-ketoglutarate dehydrogenase , malate dehydrogenase

Answer 15

niacin as NAD+

Question 16

galactosemia caused by inherited defects

Answer 16

galactokinase, uridyl transferase, or 4-
epimerase