Pancuronium

Question 1

What is the brand name of Pancuronium Bromide?

Answer 1

Pavulon

Question 2

What is the drug class of Pancuronium?

Answer 2

Non Depolarizing Neuromuscular Paralytic

Question 3

Indications for Pancuronium

Answer 3

Induction or maintenance of paralysis after intubation to assist ventilations. Rapid Sequence Intubation (RSI)

Question 4

Mechanism of Action of Pancuronium

Answer 4

Binds to the receptor for acetylcholine at the neuromuscular junction, producing skeletal muscle paralysis without fasiculations

Question 5

Contraindications for Pancuronium

Answer 5

Hypersensitivity, inability to control airway and/or support ventilations with oxygen and positive pressure, neuromuscular disease (myasthenia gravis), hepatic or renal failure

Question 6

Adverse effects of Pancuronium

Answer 6

Weakness, prolonged neuromuscular block, bronchospasm, apnea, respiratory failure, tachydysrhythmias, transient hypotension, hypertension, PVCs, salivation

Question 7

Precautions of Pancuronium

Answer 7

Tachycardia will be enhanced when used. With positive chronotropic drugs

Question 8

Adult dose of Pancuronium

Answer 8

0.06 to 0.1 mg/kg slow IV. Repeat every 30 – 60 minutes as needed

Question 9

Pedi dose of Pancuronium

Answer 9

0.04 to 0.1 mg/kg slow IV/IO

Question 10

Duration of action and onset

Answer 10

Onset – 30 seconds with peak effect of paralysis in 3 to 5 minutes
Duration of 45 to 60 minutes.