Methylprednisone Flashcards
Brand name of Methylprednisone
Solu-Medrol
Drug class of Solu-Medrol
Corticosteroid
Indications of Solu-Medrol
Acute spinal cord trauma, anaphylaxis, asthma, COPD
Mechanism of Action of Solu-Medrol
Highly potent synthetic glucocorticoid that suppresses acute and chronic inflammation; potentiates vascular smooth muscle relaxation by beta-adrenergic agonist.
Contraindications of Solu-Medrol
Premature Infants, systemic fungal infections, use with caution in patients with gastrointestinal bleeding
Adverse effects of Solu-Medrol
Depression, euphoria, headache, restlessness, seizure, increased ICP, pulmonary tuberculosis, hypertension, CHF, NV, peptic ulcer, fluid retention, hypernatremia (high sodium), hyperkalemia (increased potassium loss)
Precautions of Solu-Medrol
Will cause elevated glucose levels by
Inhibiting insulin production
Adult dose of Solu-Medrol for respiratory emergencies (asthma/COPD/anaphylaxis)
1 to 2 mg/kg IV
Adult dose of Solu-Medrol for spinal cord trauma
30 mg/kg IV over 30 minutes followed by infusion
Pedi dose of Solu-Medrol for asthma/anaphylaxis
2 mg/kg IV/IO/IM with max dose of 60 mg.
Pedi dose of Solu-Medrol for spinal cord trauma
same thing as an adult