Pancreatitis Flashcards
What 3 main substances does the pancreas make
Bicarbonate, digestive enzymes and insulin
Function of bicarbonate
Neutralizes gastric acid as meal enters small intestine
Fnctn of digestive enzymes
Turn meal to liquid for absorption
Fnctn of insulin
Signals the body to store ingested nutrients.
What cells secrete glucagon, insulin and somatostatin
Glucagon-alpha
Insulin-Beta
Somatostatin-Delta
What do basophilic cells make
Pancreatic lipase and amylase
Number one cause of pancreatitis
Alcohol in US, gallstones worldwide
Classic presenting history of pancreatitis
Acute onset persistent abdominal pain with nausea and vomiting, pain radiates to back, poor appetite, constant, pain somewhat decreased with leaning forward, +/- febrile, may have hx of alcohol, gallstones, cholesterole problems
How do you treat pancreatitis
NPO, hydration with normal saline or LR (6-12 L in first 24 hours) , pain control, antibiotics (if needed), enteral nutrition (if needed)
How long for clinical resolution of pancreatitis
3-7 days, exocrine function may take months
After severe pancreatitis, some pts…
develop diabetes, have persistent pain, have chronic diarrhea, malnourishment