Colon Cancer Flashcards
1
Q
What sequence leads to development of colon cancer
A
Adenoma-Carcinoma Sequence
2
Q
Disease with APC gene mutation on Chrom 5q. Develop thousands of polyps
A
Familial Adenomatous Polyposis
3
Q
Problem in hereditary nonpolyposis colon cancer
A
Mismatch repair gene defects.
4
Q
Screening for colon cancer
A
Big 3 are colonoscopy, flexible sigmoidoscopy, high sensitivity guaiac or immunochemical fecal occult blood test
5
Q
Gold standard for screening
A
Colonoscopy
6
Q
Colonoscopy recommended every how many of years
A
every 10 years. Alternatively, flexible sigmoidoscopy every 5 years with high sensitivity FOBT every 3 years
