Pancreatitis Flashcards
pancreatitis
the inappropriate activation of pancreatic enzymes, inflammation of the pancreas resulting in autodigestion of the pancreas and damage to peri-pancreatic tissues and vascular network
______ response causes further damage to the pancreas
inflammatory response
causes and risk factors of pancreatitis
- gallstones
- alcohol
- pregnancy
- administration of TPN
- surgery
- AIDS
- medication complications
- hypercalcemia and or significant hypertriglyceridema
- specific genetic mutations
chronic pancreatitis
progressive obstruction of exocrine functions
- irreversible
- may demonstrate diabetes
- malabsorption syndrom
why might chronic pancreatitis demonstrate diabetes
b/c of destruction of insulin producing cells
acute pancreatitis has a _____ onset
sudden onset
symptoms of acute pancreatitis
- abdominal pain
- abdominal tenderness
- hypotension
- respiratory distress
- abdominal distention
- poor urine output
- tachycardia
- signs of hypocalcemia
3 forms of acute pancreatitis are
mild form, more severe form, severe form
mild form of acute pancreatitis
- called institutional or edematous pancreatitis
- resolves in 5-7 days
more severe form of acute pancreatitis
extensive necrosis
severe form of acute pancreatitis
- local and systemic complications
- 25-30% mortality rate with complications and co morbidities
1st phase of pancreatitis
trypsin and other enzymes released
2nd phase of pancreatitis
intrapancreatic inflammation
3rd phase of pancreatitis
- extrapancreatic / systemic injury
- kallikrein
in pancreatitis hypocalcemia results from
necrosis