Acute & Chronic Kidney Injury Flashcards
acute renal failure / acute kidney injury (AKI)
- abrupt disease in kidney function
- a rapid, progressive process
- difficult to detect
acute renal failure is reversible if
identified and treated early
acute renal failure is identified by
oliguria and elevated serum BUN and creatinine
elevation of BUN and creatinine =
azotemia
BUN and creatinine are both products of
protein metabolism
azotemia
medical condition characterized by increase levels of nitrogen in the body
risk factors for acute kidney injury
- hx of renal problems
- hx of htn
- hx od diabetes
- use of nephrotoxic agents
- exposure to heavy metals or organic solvents
- recent hypotensive episode
- tumor or vascular obstruction
- infection
-sepsis
common causes of acute kidney injury
- arterial occlusion
- absolute decrease in effective in blood volume
- relative decrease in blood volume
prerenal injury
caused by renal blood flow resulting in renal hypoperfusion and ischemia
prerenal injury causes a decreases in the
GFR
pre renal injury is often reversible? or irreversible?
reversible
causes of prerenal injury
- decreased cardiac output
- increased vascular capacity
- drugs that alter renal hemodynamics
acute tubular necrosis (ATN) is a type of _____ renal injury
intrinsic renal injury
what is acute tubular necrosis (ATN)
destruction of renal tubular epithelial cells
ATN is caused by
- ischemia
- sepsis
- vascular problems (such as malignant htn)
- acute glomerulonepritis and other infections
- drug allergies and toxicity
- rhabdomyolosis (breakdown of skeletal muscle and release of myoglobin which plugs glomeruli)
2 types of ATN
(1) ischemic
(2) toxic
ischemic ATN
prolonged hypoperfusion
(surgical procedure, anasthesia)
toxic ATN
from aminoglycoside anti-infectives, contrast induced nephropathy (CIN)
oliguric ATN
less likely to recover renal function
- has a high mortality rate
non-oliguric ATN
commonly seen with toxic injury
- renal concentrating defect
- hyperkalemia common complication
postrenal injury
caused by an obstruction to the outflow or urine from the kidneys
obstruction to one kidney does not likely lead to renal failure unless
the other kidney is not functioning or absent
uremia occurs when
2/3 of total number of nephron loss
fluid overload can lead to
HF, pulmonary edema, hear crackles
wastes can cause
homeostasis and anemic disorders when there are extra wastes
nursing care for AKI and fluid volume overload
diuretics, fluid restriction as prescribed, monitor for S&S of fluid volume excess, intake and output, oral care, ice chips
possible neurologic symptoms in pt with AKI
decreased mental function, peripheral neuropathy, cerebral edema
possible cardiovascular and pulmonary symptoms in pt with AKI
htn, pulmonary edema, electrolyte imbalance, pneumonia
possible GI symptoms in pt with AKI
poor appetite, GI bleeding, constipation, diarrhea
possible hematologic symptoms in pt with AKI
anemia, blood clots
possible integumentary symptoms in pt with AKI
pale appearance, bruising, pruritis, dry skin, thin hair, brittle nails, uremic frost
possible skeletal symptoms in pt with AKI
usteodystrophy