Pancreatic Cancer VS similar presentation CAs Flashcards
Pancreatic cancer cxfx + 1 risk factor
Painless jaundice with
weight loss
+/– depressive symptoms
History of smoking
Pancreatic cancer Etiology (patho)
90% adenocarcinoma of the pancreatic head with common bile duct dilatation
Pancreatic cancer Most accurate test
CT scan of the chest,
abdomen, and pelvis (also used for staging)
Pancreatic cancer: CA 19-9 is used to __
measure response to therapy. also for Cholangiocarcinoma
Pancreatic cancer tx
Pancreaticoduodenectomy
(Whipple procedure)
Palliative CBD duct stent
(for metastatic disease)
Cholangiocarcinoma cxfx
Painless jaundice with weight loss in patient with history of PSC
Cholangiocarcinoma epidemiology
The most common cancer of the bile duct
Cholangiocarcinoma, how is alkaline phosphatase
Elevated
Cholangiocarcinoma Etiology and epidemiology too
Most commonly PSC Southeast Asians at risk due to Clonorchis sinensis and Opisthorchis viverrini
Cholangiocarcinoma Most accurate
imaging test
(to
localize mass):
MRCP
Cholangiocarcinoma DX
ERCP with brushings or FNA allows for biopsy
Cholangiocarcinoma Tx
Surgical resection if
possible and
chemotherapy
Gallbladder cancer cxfx
Constant RUQ pain and jaundice when metastasis occurs
Palpable “porcelain gallbladder”
Gallbladder cancer etiology
90% from adenocarcinoma
Gallbladder cancer epidemiology
More common
in women