Pancreatic Cancer Flashcards
1
Q
Most common pancreatic tumour
A
Adenocarcinoma
At head of pancreas
2
Q
Associations
A
Age Smoking Diabetes Chronic pancreatitis Hereditary non-polyposis colorectal carcinoma Multiple endocrine neoplasia BRCA2 gene
3
Q
Features of pancreatic cancer
A
- painless jaundice
- Courvoisier’s law
- loss of exocrine function = steatorrhoea
- loss of endocrine function = DM
- atypical back pain
- migratory thrombophlebitis
4
Q
Courvoisier’s law
A
In painless obstructive jaundice a palpable gallbladder is unlikely to be due to gallstones
5
Q
What is Trousseau sign characteristic of?
A
Migratory thrombophlebitis
6
Q
Ix
A
US
High resolution CT is first choice if diagnosis supected
7
Q
Management
A
Little suitable for surgery
Whipple’s resection if resectable lesion in head of pancreas
Adjuvant chemo post surgery
ERCP with stenting for palliation
8
Q
Whipple’s resection
A
Pancreaticoduodenectomy
9
Q
Side effects of Whipple’s resection
A
Dumping syndrome
Peptic ulcer disease
