Pancreatic Cancer Flashcards
Most common type of pancreatic cancer
Pancreas ductal adenocarcinoma
Most common location of an pancreatic cancer
Head of pancreas
Key presenting feature of pancreatic cancer
obstructive jaundice
what causes the obstruc jaundiuce in pancreatic cancer
compression of the bile duct from the pancreatice tumour
PBLL
Pancreatice cancer metastasise sites
- Peritoneum
- Bones
- Lungs
- Liver
Advanced pancreatic cancer avr. survival rate
6 months
5-yr survival rate of pancreatic cancer
approx. 10%
Pancreatice cancer clinical presentations
- Painless obstructive jaundice
- Dark urine
- Pale stools
- Itchiness
- Abdo pain / flank pain
- Nausea / vomiting
- Unitentional WL
Pancreatice cancer signs
- Palpable mass
- Abdo / flank pain
- Hyperglycaemia
- New onset DM
- Nausea / Vomiting
- Changes to bowel habits
Pancreatic cancer 2WW referral criteria
- > 40 w/ jaundice
- > 60 w/ WL + additional Sx
Dx Ix for pancreatic cancer
- CT Abdomen
- Histology - Bx
Define Courvoisier’s law
- Jaundice
-
Enlarged/palpable gallbladder
(Pancreas / biliary tree malignancy strongly suggested)
Gallstones unlikely
Trousseau’s sign malignancy
Migratory Thrombophlebitis
related to pancreatice adenocarcinoma
what is the Trousseau’s sign malignancy assoc. with
Pancreatic adenocarcinoma
Pancreatic cancer marker
CA 19-9
non-specific to pancreatic cnacer
Pancreatic Ix
- CT CAP - for staging / metastases
- CA 19-9 - cancer marker
- MRCP - Assess HPB system
- ERCP - procedure to stenting to relief obstructive juandice or obtain Bx from tumour
Head of the pancreas lesions Mx
Whipple’s procedure - pancreaticoduodenectomy
tumour not spread
Modified Whipple
Preserving the pylorus of the stomach
