Pancreatic cancer

Question 1

what type of cell are majority of pancreatic cancers?

Answer 1

Adenocarcinoma

Question 2

How does it present?

Answer 2

PAINLESS OBSTRUCTIVE JAUNDICE:
pale stools, dark urine, itching

Weight loss
Palpable mass in epigastrium
Upper abdo or back pain
Change in bowel habit
NV
New onset diabetes or sudden worsening type 2 diabetes

Question 3

When can GP refer for a direct access CT abdomen?

Answer 3

Weight loss plus any of:

Diarrhoea
Back pain
Abdominal pain
Nausea
Vomiting
Constipation
New-onset diabetes

Question 4

What is Courvoisiers law?

Answer 4

Palpable GB along with jaundice is unlikely to be gallstones

Question 5

What is Trousseaus sign?

Answer 5

Migratory thrombophlebitis as a sign of malignancy

Question 6

What tumour marker is it associated with?

Answer 6

CA19-9

Question 7

what is initial investigation ?

Answer 7

Staging CT TAP

Question 8

What is a Whipples procedure?

Answer 8

Surgical operation to remove a tumour of the head of the pancreas that hasn’t spread
MASSIVE operation - removes head of pancreas, pylorus of stomach, duodenum, GB, bile duct, LNs