Pancreas Flashcards
Alpha cells secrete…
Glucagon
Beta cells secrete…
Insulin
Gamma cells secrete…
Somatostatin
E cells secrete…
Ghrelin
F cells secrete…
Pancreatic polypeptide
What does the blood supply first in the pancreas
Beta cells
Where are immature Beta cells found
At the periphery of islets
What stimulates the release of acetylcholine in the pancreas
The vagus nerve
When glucagon binds to its receptor on the liver, it causes an increase in ____ and a decrease in ____
Increase: gluconeogenesis and glycogenolysis
Decrease: glycolysis and glycogenesis
What inhibits the activation of glycogen synthase
Glucagon and epinephrin
What stimulates the activation of glycogen synthase
Insulin and glucose/G6P
What is the only hormone that lowers blood glucose
Insulin
Insulin receptor is…
RTK
Glucagon and epinephrine receptors are…
GPCR
3 key target tissues of insulin
Liver, muscle and adipose