Pancreas Flashcards

0
Q

Failure of fusion of the fetal duct system of the dorsal and ventral pancreatic primordia

A

Pancreas divisum

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1
Q

Bandlike ring of pancreatic tossue encircling the 2nd portioon of duodenum

A

Annular pancreas

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2
Q

Features of pancreatitis

A

Tissue proteolysis
Lipolysis
Hemorrhage

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3
Q

Most common causes of pancreatitis

A

Cholelithiasis

Alcoholism

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4
Q

Mutation that leads to a loss of site in trypsin that is needed for its inactivation

A

Cationic trypsinogen gene PRSS1

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5
Q

Mutation that leads to a defective protein that can NO LONGER AINHIBIT trypsin

A

Serine protease injibitor, kazal type 1 SPINK1 gene

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6
Q

Tissue liquefaction creates what ?

A

Pancreatic abscesses sterile

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7
Q

Localized collection of necrotic hemorrhagic material rich in pancreatic enzymes

A

Pancreatic pseudocyst

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8
Q

Pancreatic cyst with kidney and liver cysts

A

Congenital polycystic disease

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9
Q

Pancreatic cyst with angiomas of cns

A

Von hippel lindau disease

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10
Q

Well circumscribed nodules with central stellate cell scar
Solitary
Cuboidal epithelium
Glycogen

A

Serous cystadenoma

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11
Q

Mucin producing tall columnar lining
Women
Tail of the gland

A

Mucous cystic neoplasm

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12
Q

Involve larger pancreatic ducts
Mucin oozing from a patulous ampulla of vater
Head of gland

A

Intraductal papillary mucinous neoplsm

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13
Q

Round tumors with solid and cystic regioons
In adolescent snd less than 35 yo women
Surgical resection

A

Solid pseudopapillary tunor

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14
Q

Precursor of pancreatic adenocarcinoma

A

Pancreatic intraepithelial neoplasia

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15
Q

Gene mutations in pancreatic cancer

A

KRAS oncogene

P16 / cdkn2A

16
Q

Pancreratic cancer with osteoclast like giant cells

A

Undifferentiated carcinoma

17
Q

Tumor of childhood with acinar differentiation and squamoid nests

A

Pancreatoblastoms