Liver Function Tests Flashcards

0
Q

AST or SGOT fxn

A

Aspartate aminotransferase under HEPATOCYTE INTEGRITY AND FUNCTION

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1
Q

What 2 tests under serum bilirubin levels

A

Total bilirubin

Unconjugated/indirect bilirubin

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2
Q

ALT or SGPT fxn

A

Alanine aminotransferase under HEPATOCYTE INTEGRITY AND FUNCTION

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3
Q

LDH fxn

A

Lactate dehydrogenase under HEPATOCYTE INTEGRITY AND FUNCTION

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4
Q

3 tests for protein synthesis

A

Serum albumin
Prothrombin time
Total serum protein

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5
Q

Alk phos fxn

A

Alkaline phosphatase under BILIARY OBSTRUCTION

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6
Q

GGT fxn

A

Gamma glutamyltransferase under BILIARY OBSTRUCTION

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7
Q

5-NT fxn

A

5 nucleotidase under BILIARY OBSTRUCTION

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8
Q

AST sources

A

Liver and heart

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9
Q

ALT source

A

Hepatocytes ONLY

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10
Q

LDH source

A

Too many! LDH in liver are LDH4 and LDH5

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11
Q

ALk phos source

A

Liver bone intestine

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12
Q

GGT source

A

Hepatobiliwry, renal tubular and pancreatic epithelia

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13
Q

5NT source

A

Hepatobiliary ONLY

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14
Q

Describe levels of glucose, wbc, plt and serum albumini n FULMINANT HEPATIC FAILURE

A

Low glucose, high wbc, low plt and low serum albumin

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15
Q

PT and serum total bilirubin in CHRONIC HEPATIC FAILURE

A

Pt >30 secs

Total bili >17.5 mg/dl

16
Q

Biopsy findings in LIVER CIRRHOSIS

A

Nodules and fibrous septa

17
Q

Unique immuno findings in PRIMARY BILIARY CIRRHOSIS

A

Anti mitochondrial antibodies 95%

Increase igM