PANCREAS Flashcards
Describe the gross and microscopic anatomy of the pancreas along with their secretions and functions
Pancreas
- spongy retroperitoneal gland posterior to the greater curvature of the stomach
- measure 12 to 15 cm long, and 2.5 cm thick
- has head encircled by duodenum, body, midportion, and a tail on the left
Endocrine and exocrine gland
- Endocrine portion—pancreatic islets that secrete insulin and glucagon
- Exocrine portion—99% of pancreas that secretes 1,200 to 1,500 mL of pancreatic juice per day
–Secretory acini release their secretion into small ducts that converge on the main pancreatic duct
Pancreatic duct
runs lengthwise through the middle of the gland
joins the bile duct at the hepatopancreatic ampulla
hepatopancreatic sphincter controls release of both bile and pancreatic juice into the duodenum
Accessory pancreatic duct
smaller duct that branches from the main pancreatic duct
opens independently into the duodenum
bypasses the sphincter and allows pancreatic juice to be released into duodenum
Pancreatic juice
alkaline mixture of water, enzymes, zymogens, sodium bicarbonate, and other electrolytes
acini secrete the enzymes and zymogens
ducts secrete bicarbonate–bicarbonate buffers HCl arriving from the stomach
Other pancreatic enzymes
pancreatic amylase: digests starch
pancreatic lipase: digests fat
ribonuclease and deoxyribonuclease: digest RNA and DNA respectively