Palate development Flashcards

1
Q

when does the palate form?

A

weeks 6-12

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2
Q

where is the primary palate derived from?

A

fused medial nasal prominences

intermaxillary segment

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3
Q

what pushes together the medial nasal prominences?

A

maxillary prominences

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4
Q

contents of the primary palate?

A

premaxillary segment of maxilla
- 4 incisors
- incisive canal

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5
Q

describe intramembranous ossification

A

mesenchymal cells become osteoblasts
osteoblasts deposit osteoid
mineral deposited
osteoblasts trapped become osteocytes
osteocytes form bone

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6
Q

when does secondary palate begin to form?

A

week 8

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7
Q

what are the palatine shelves formed via?

A

outgrowths of maxillary prominences

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8
Q

stages of secondary palate formation?

A

shelves project on either side of tongue
mandible grows
tongue grows down
shelves grow towards midline
shelves fuse = 2nd palate

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9
Q

contents of secondary palate?

A

palatine segment of maxilla and palatine bone

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10
Q

knocking out of what gene results in cleft palate?

A

TGFB3

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