Development and Disorder Flashcards

1
Q

describe developmental biology

A

the study of the processes by which organs grow and develop

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2
Q

what is the process in which an undifferentiated cell is instructed by specific organisers to produce a morphogenic effect?

A

induction

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3
Q

what state are stem cells in?

A

undifferentiated

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4
Q

when is the preimplantation period?

A

first week

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5
Q

when is the embryonic period?

A

week 2-8

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6
Q

when is the fetal period?

A

week 3- month 9

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7
Q

what events occur during preimplantation?

A

fertilisation
implantation

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8
Q

what events occur during the embryonic week?

A

induction
proliferation
differentiation
morphogenesis
maturation

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9
Q

what events occur during fetal period?

A

maturation

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10
Q

what is the action of one group of cells on another that leads to the establishment of the developmental pathway in the responding tissue?

A

induction

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11
Q

what is controlled cellular growth and accumulation of byproducts?

A

proliferation

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12
Q

what is the change in identical embryonic cells to become distinct structurally and functionally?

A

differentiation

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13
Q

what is the development of specific tissue structure or differing form dye to embryonic cell migration or proliferation and inductive interactions?

A

morphogenesis

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14
Q

what is the attainment of adult function and size due to proliferation, differentiation, and morphogenesis?

A

maturation

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15
Q

what physiologic processes/ spatial and temporal events occur during the embryonic period?

A

patterning

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16
Q

during the embryonic period, what develops into an embryo?

A

the blastocyst

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17
Q

what is the cystodifferentiation?

A

development of different cell types

18
Q

what is histodifferentiation?

A

development of different histologic tissue types within a structure

19
Q

what is morphodifferentiation?

A

development of differing morphology which makes up its structure or shape, for each organ or system

20
Q

what is morphogenesis?

A

development of specific tissue structure or shape

21
Q

when does an embryo become recognizable?

A

week 8 of prenatal development

22
Q

when do the embryonic cell layers (germ layers) appear within the blastocyst?

A

second week of prenatal development

23
Q

where does the ectoderm originate?

A

epiblast layer

24
Q

where does the mesoderm originate?

A

migrating cells from epiblast layer

25
where does the endoderm originate?
migrating cells from epiblast layer
26
where do neural crest cells originate?
migrating neuroectoderm
27
what does the ectoderm form?
epidermis - sensory epithelium of eyes, ears, nose, NS, and neural crest cells; mammary and cutaneous glands.
28
what does the mesoderm form?
dermis, muscle, bone, lymphatics, blood cells and bone marrow, cartilage, reproductive, and excretory organs.
29
what does the endoderm form?
respiratory and digestive system linings, liver, pancreatic cells.
30
what do neural crest cells form?
components of NS pigment cells, connective tissue proper, cartilage, bone, and certain dental tissue
31
what forms week 2, and is a circular plate of bilayered cells?
bilaminar embryonic disc
32
what does the bilaminar disc thicken to become in week3?
trilaminar embryonic disc
33
what layers does the trilaminar disc form?
mesoderm embryonic endoderm ectoderm
34
when does the epiblast layer become considered as the ectoderm?
week 3
35
what happens to the embryonic disc during week4?
embryonic folding
36
what does embryonic folding result in?
proper tissue type position
37
what type of interactions occur after week4?
dynamic, reciprocal, and sequential
38
what general types of phenomena are tissue interactions associated with?
instructive permissive
39
during organogenesis, how is organ rudiment formed?
morphogenesis and proliferation
40
during organogenesis, how are organ specific structures formed?
differentiation
41
what is required for palatal shelves to fuse?
TGF B3
42
when TGF B3 is knocked out, what is not produced?
hylauronic acid - HAS1