Pain relief Flashcards
1
Q
Morphine
A
binds opiod GPCRs inhibitin adenyl cyclase
reduces intracellular cAMP no more NT release
2
Q
naloxone
A
opiod receptor antagnosit (Mu opiod)
3
Q
Paracetamol
A
COX-2 enzyme inhibition preventing arachodonic acid into prostaglandins
4
Q
Hyoscine butylbromide
A
Muscarinic M3 R antagonist
preventing Ach release and binding in GIT
smooth muscle relaxation
5
Q
NSAIDs
A
Inhibit prostaglandin E synthesis
block hypothalamus activation during inflammation and temp rise
