cardioresp drugs Flashcards
1
Q
Endothelin receptor antagonist
A
Bosentan
potent vasoconstrictor - increase vascular tone
polypeptide
used in pulm HTN
2
Q
Aminophylline
A
phosphodiesterase T3 antagonist (and T4)
bronchodilation of smooth muscle
suppresion of airway response to stimuli
theophyline and ethylendiamine
(adenosine T2 antagonist inhibits airway PNS)
3
Q
Isoniazid MOA
A
inhibitis myocolic acid synthesis interfering with cell wall synthesis
4
Q
verapamil
A
rate limiting calcium channel blocker
constipation
5
Q
What is NO derived form
A
L argenine by NO synthase
6
Q
MOA NO
A
Increases cGMP
7
Q
GTN
A
synthetic compound which breaks down into NO
SE: headaches, low BP, rapid systemic vasodilatio
8
Q
SE protsglandin E1
A
apnoea
respiratory depression
tissue oedema
fever
seizures
tachycardia
hypoglycaemia
