Anti-epileptics Flashcards

1
Q

Benzodiazepines

A

Bints post synaptic GABA ligand gated CHLORIDE channels
Increases chloride causing hyperpolarisation and stabelisation

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2
Q

TCAs

A

Block serotonin and norepinephrine reuptake increase NT concentrations

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3
Q

Phenytoin

A

non specific sodium channel blocker
primary site of action is in the motor cortex
used in status

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4
Q

Sodium valproate

A

Enhances GABA inhibition by increasing GABA concentrations and blocking SODIUM channels

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