Antibacterials/virals/fungals Flashcards
1
Q
Isoniazid
A
Interefere with mycolic synthesis effecting cell wall synthesis
2
Q
Amikacin
A
aminoglycoside
interferes with mRNA and tRNA recoptof binding sites
used in drug resistant TB
3
Q
Ethambutol
A
Inhibits aribinosyltransferases
prevent formation of bacterial cell wall components and cell devision
4
Q
Rifampacin
A
inhibits DNA dependent RNA polymerase inhibit bacterial RNA synthesis - cell death
5
Q
Pyrazinamide
A
interferes with fatty acid synthesis required for growth and replication
6
Q
Clarithromycin
A
potent enzyme inhibitor and can icnrease cyclosporin levels- dose will need to be reduced
7
Q
A
