Pain Pharmacology Flashcards
1
Q
Pain Pathway
A
2
Q
NSAIDs
A
Inhibit prod. of prostaglandins by inhibiting cyclooxygenase
3
Q
Effects of Inhibiting COX-1
A
- GIT ulceration
- Airway Constriction
- Renal toxicity
- Platelet dysfunction
4
Q
Effects of Inhibiting COX-2
A
- Reduced pain/inflammation
- increased risk of MI, Stroke, Blood clots
5
Q
NSAID Examples
A
6
Q
SAIDs
A
Steroids:
- Hormones synth. in kidney adrenal glands
Glucocorticoids:
- Anti-inflammatory & Immunosuppressive agents
7
Q
Corticosteroids Method of Action
A
- Inhibition of Phospholipase A2
8
Q
Important Glucocorticoids
A
