Local Anaesthetics Flashcards
1
Q
Method of Action of Local Anaesthetics
A
- Binds directly to intracellular part Sodium Channels
- Prevent influx of Na+-> Stop depol. of axons so pain can-t go to brain
- Reverse Inhibition
2
Q
Factors Affecting of Local Anaesthetics
A
- Use Dependence
- Lipid Solubility
- Ionisation & pH
- Absorption
3
Q
Adverse Effects of Amide & Ester
A
4
Q
Core LAs & Side Effects
A
5
Q
Amides vs Esters
A