Pain Patho Flashcards
Dysesthesia
abnormal sensation described as unpleasant
Hyperalgesia
Exaggerated pain response from normally painful stimulus
-aspects of summation w/ repeated stimulus of constant intensity/ aftersenation
Hyperesthesia
exaggerated perception of touch stimulus
Allodynia
abnormal perception of pain
from normally non-painful mechanical or thermal stimulus
usually delay in perception
Hypoalgesia
< sensitivity and
raised threshold to painful stimuli
Anesthesia
Reduced perception of all sensation
(mainly touch)
Analgesia
Reduced perception of pain stimulus
Paresthesia
spontaneous abnormal sensation,
not necessarily unpleasant
“pins and needles”
Causalgia
Burning pain in the distribution of 1 or more peripheral nerves
Fast Pain
- Fiber?
- Sensation?
thin myelinated A-delta fibers
sharp, pricking, electric pain
Feel 0.1 sec after stim
Slow Pain
- Fiber?
- Sensation?
Unmyelinated, C fibers
Slow burning, aching, throbbing, chronic
felt 1 sec after stim
3 Types of Painful Stimuli?
Which 1 is only slow pain?
no fast
Mechanical
Thermal
Chemical (only slow)
Chemical Painful Stimuli
sensitizing chemicals
Bradykinin Acetylcholine Prostaglandins Substance P Proteolytic Enzymes
^ activate nociceptors =
generate action potential
Nociception
- Transduction
Noxious Stimuli
Convert to electric activity @ sensory nerve endings
Nociception
- Transmission
Propagation of impulses thru sensory nervous system
Nociception
-Modulation
Process of transmission modified by neural influences
Neuron originate in brainstem,
release substance in spinal cord to inhibit nociceptive impulses
Nociception
-Perception
Transduction + Transmission + Modulation
work w/ pt psychology to create what is perceived as pain
Conscious experience of pain
Primary Afferent Neurons
2 types
1st Order
2nd Order
